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Neukine 300mcg Injection PFS

Prescription Required
prescription
Cold Chain
cold chain

Salt Composition

Manufacturer

INTAS PHARMACEUTICALS LTD

Origin of Medicine

India

₹600.00

Inclusive of all taxes

Save ₹ 639.17 (52%)
MRP:₹1239.17

₹600.00

    MRP:₹1239.17
Save ₹ 639.17 (52%)
1 Prefilled Syringe(s) Of 1ml

1 Prefilled Syringe(s) Of 1ml

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Overview & Usage

Overview

Neukine 300mcg Injection contains filgrastim, a medicine that helps the body make more white blood cells. It is mainly used to reduce the risk of infections and fever in people receiving chemotherapy for non-myeloid cancers. It also helps shorten the period of low white blood cells in patients with acute myeloid leukemia.

This injection is also given to people undergoing bone marrow transplants, those with severe chronic neutropenia, and patients preparing for leukapheresis. It can improve survival in individuals exposed to high levels of radiation that damage the bone marrow. Additionally, it may be used in people with advanced HIV infection to help lower infection risk.

Neukine belongs to the colony-stimulating factor group of medicines, which support white blood cell production. Since chemotherapy can lower these cells, this medicine helps the body fight infections more effectively. Inform your doctor if you have kidney or liver problems, sickle cell anemia, or bone conditions. Common side effects include fever, pain, cough, rash, nosebleeds, and shortness of breath.


Usage

1. Boosts white blood cells during chemotherapy

2. Lowers infection and fever risk (febrile neutropenia)

3. Shortens low WBC duration in acute myeloid leukemia

4. Supports recovery after bone marrow transplant

5. Treats severe chronic neutropenia

6. Helps mobilize stem cells for leukapheresis

7. Aids survival after high-dose radiation exposure

8. Reduces infection risk in advanced HIV infection

Pharmacological Effects

Neukine 300mcg Injection boosts the production and function of neutrophils, the white blood cells that help fight infections. By stimulating the bone marrow, it reduces the duration of low white blood cell counts during chemotherapy, bone marrow transplants, or severe chronic neutropenia. It also helps mobilize stem cells into the bloodstream for collection during leukapheresis, improving the body’s overall immune response.


Side Effects

Side Effects of Neukine 300mcg Injection

Serious Side Effects (Seek immediate medical attention):

  • Severe allergic reactions (swelling of face/lips, difficulty breathing, severe rash)
  • Spleen enlargement or rupture (left upper abdominal or shoulder pain)
  • Shortness of breath or lung problems
  • Severe or persistent fever
  • Kidney problems (changes in urine, swelling)
  • Sickle cell crises in patients with sickle cell disease
  • Irregular heartbeat or chest pain

Common Side Effects (Usually mild and temporary):

  • Fever
  • Bone pain or muscle pain
  • Headache
  • Rash or redness
  • Cough
  • Fatigue or weakness

Dosage

The dosage of Neukine 300mcg Injection depends on the patient’s condition and body weight. It is usually given as a daily injection under the skin or into a vein, as directed by a healthcare professional. Your doctor will decide the exact dose and duration based on your white blood cell count and response to treatment. Never adjust or stop the dose on your own.


Safety Advice For Neukine 300mcg Injection

Breast Feeding

Breast Feeding

Unsafe

Use with caution. It is not known if the medicine passes into breast milk. Consult your doctor before breastfeeding.

Breast Feeding

Alcohol

Consult Your Doctor

No specific interaction is known, but it is best to avoid or limit alcohol to prevent additional strain on the body during treatment.

Breast Feeding

Lungs

Consult Your Doctor

Use with caution if you have lung problems. Report symptoms like cough, chest pain, or breathing difficulty immediately.

Breast Feeding

Driving

Unsafe

Avoid driving if you feel dizzy, tired, or unwell after the injection.

Breast Feeding

Pregnancy

Safe

Use only if clearly needed. Inform your doctor if you are pregnant or planning to conceive.

Storage Advice

  • Store in a refrigerator (2 - 8°C)
  • Do not freeze
  • Keep out of reach of children and pets

  • FAQs about Neukine 300mcg Injection

    Q1. What is Neukine 300mcg Injection used for?

    It is used to increase white blood cell count, reduce infection risk during chemotherapy, treat severe chronic neutropenia, support bone marrow recovery, and prepare stem cells for leukapheresis.

    Q2. How does Neukine work?

    Neukine contains filgrastim, which stimulates the bone marrow to produce more neutrophils, a type of white blood cell that helps fight infections.

    Q3. How is Neukine given?

    It is administered as an injection under the skin (subcutaneous) or into a vein (IV) by a healthcare professional.

    Q4. What are the common side effects of Neukine ?

    Common side effects include fever, bone or muscle pain, headache, rash, cough, fatigue, nausea, and injection site reactions.

    Q5. Can I use Neukine during pregnancy or breastfeeding?

    It should be used during pregnancy only if clearly needed, and breastfeeding should be done only after consulting your doctor.

    Q6. Who should avoid using Neukine?

    People with a history of severe allergic reactions to filgrastim or other serious health issues like spleen problems should avoid this injection, and patients should always inform their doctor of existing medical conditions.

    Key Fact Box

    Active ingredient Filgrastim
    Pharmacologic class colony-stimulating factor
    Medication category Hematopoietic
    Dosage forms Injection

    Medical Advisory

      The information on the Phoenix Pharmex website is shared for educational purposes only and is not a substitute for professional medical advice or treatment. Always consult a doctor for any health-related questions. Please avoid self diagnosis or delaying medical care based on this content. Our mission is to support informed decisions not replace professional medical guidance.

    DOSAGE

    Frequently Asked Questions

    Azadine 100mg Injection contains Azacitidine which belongs to the group of medicines called Anticancer agents. It is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Azadine 100mg Injection is typically used in adults who cannot undergo stem cell transplantation. It may be also used to treat other conditions, as determined by the doctor.

    Azadine Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised.

    You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.

    Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.

    MEDICINAL USE OF AZADINE 100MG INJECTION

    Azadine 100mg Injection is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    It is used to treat:

    • All sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow)
    • Chronic myelomonocytic leukemia (CMML; blood cancer of monocytes)
    • Acute myeloid leukemia (AML; blood cancer of WBC)
    SIDE EFFECTS OF AZADINE 100MG INJECTION

    Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

    • Low RBC count causing anemia, tiredness and pale skin
    • Increased infections, lung infections (pneumonia), fever and chills
    • Increased bleeding tendency due to low blood platelet counts
    • Nausea, vomiting
    • Diarrhea, constipation, loss of appetite, stomach pain
    • Tiredness, weakness
    • Injection site reactions (such as pain, redness and swelling or lump formation)
    • Joint pain, muscle pain, skin rashes with redness and itching
    • Sore nose and throat, cold sores, sinnusitis
    • Headache, dizziness
    • Trouble sleeping (insomnia)
    • Nosebleeds, bleeding gums
    • Weight loss
    • Urinary tract infections
    • Ulcers of mouth or tongue
    • High or low blood pressure
    • Anxiety, confusion
    • Hair loss, dehydration
    • Oral fungal infection
    • Sleepiness
    • Fluid around the lungs or heart
    DOSAGE OF AZADINE 100MG INJECTION
    • The dose of Azacitidine is determined by the patient's height, weight, and general condition. It is given under the skin of your thigh, stomach, or upper arm.
    • Minimum of 4 to 6 cycles; may continue treatment if the patient continues to benefit.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified health care professional, the likelihood of a missed dose is very low.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

    Ques 1: What is the use of AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Ques 2: How does AZADINE 100MG INJECTION works?

    Ans :AZADINE 100MG INJECTION is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    Ques 3: Can I take AZADINE 100MG INJECTION during breastfeeding?

    Ans :No. AZADINE 100MG INJECTION is not recommended for use in breast-feeding women. Therefore, inform your doctor before receiving it.

    Ques 4: Can AZADINE 100MG INJECTION increase the risk of infections?

    Ans :AZADINE 100MG INJECTION may cause a drop in the number of white blood cells in the body and may weaken your immune system. As a result, you may be at a greater risk of getting infected while receiving AZADINE 100MG INJECTION. To avoid this, your doctor will regular monitor your blood counts as a precaution. However, inform your doctor if you experience any signs of infection such as fever.

    Ques 5: Can the use of AZADINE 100MG INJECTION make me feel tired?

    Ans :Yes. AZADINE 100MG INJECTION may make you feel tired easily. This is because, it reduces the levels of red blood cells in your blood and may make you anemic. Consult your doctor if you experience tiredness after receiving AZADINE 100MG INJECTION. Tiredness can also occur if you have any pre-existing disease conditions such as liver or kidney impairment while receiving this medicine.

    Ques 6: Can I drive a car after receiving AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION may make you feel tired or weak. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by AZADINE 100MG INJECTION.

    Ques 7: How AZADINE 100MG INJECTION is administered?

    Ans :AZADINE 100MG INJECTION will be given to you only by a doctor or a nurse beneath the skin (subcutaneously) of thighs, arms or abdomen.

    Ques 8: How to control nausea caused due to AZADINE 100MG INJECTION?

    Ans :Generally, anticancer medicines are associated with uncontrollable nausea and vomiting. To avoid this, your doctor would prescribe a suitable medicine to control them along with AZADINE 100MG INJECTION. If not, consult your doctor for a suitable anti-emetic medicine. Do not self-treat nausea.

    Overview

    Neukine 300mcg Injection contains filgrastim, a medicine that helps the body make more white blood cells. It is mainly used to reduce the risk of infections and fever in people receiving chemotherapy for non-myeloid cancers. It also helps shorten the period of low white blood cells in patients with acute myeloid leukemia.

    This injection is also given to people undergoing bone marrow transplants, those with severe chronic neutropenia, and patients preparing for leukapheresis. It can improve survival in individuals exposed to high levels of radiation that damage the bone marrow. Additionally, it may be used in people with advanced HIV infection to help lower infection risk.

    Neukine belongs to the colony-stimulating factor group of medicines, which support white blood cell production. Since chemotherapy can lower these cells, this medicine helps the body fight infections more effectively. Inform your doctor if you have kidney or liver problems, sickle cell anemia, or bone conditions. Common side effects include fever, pain, cough, rash, nosebleeds, and shortness of breath.


    Usage

    1. Boosts white blood cells during chemotherapy

    2. Lowers infection and fever risk (febrile neutropenia)

    3. Shortens low WBC duration in acute myeloid leukemia

    4. Supports recovery after bone marrow transplant

    5. Treats severe chronic neutropenia

    6. Helps mobilize stem cells for leukapheresis

    7. Aids survival after high-dose radiation exposure

    8. Reduces infection risk in advanced HIV infection

    Pharmacological Effects

    Neukine 300mcg Injection boosts the production and function of neutrophils, the white blood cells that help fight infections. By stimulating the bone marrow, it reduces the duration of low white blood cell counts during chemotherapy, bone marrow transplants, or severe chronic neutropenia. It also helps mobilize stem cells into the bloodstream for collection during leukapheresis, improving the body’s overall immune response.


    Side Effects

    Side Effects of Neukine 300mcg Injection

    Serious Side Effects (Seek immediate medical attention):

    • Severe allergic reactions (swelling of face/lips, difficulty breathing, severe rash)
    • Spleen enlargement or rupture (left upper abdominal or shoulder pain)
    • Shortness of breath or lung problems
    • Severe or persistent fever
    • Kidney problems (changes in urine, swelling)
    • Sickle cell crises in patients with sickle cell disease
    • Irregular heartbeat or chest pain

    Common Side Effects (Usually mild and temporary):

    • Fever
    • Bone pain or muscle pain
    • Headache
    • Rash or redness
    • Cough
    • Fatigue or weakness

    Dosage

    The dosage of Neukine 300mcg Injection depends on the patient’s condition and body weight. It is usually given as a daily injection under the skin or into a vein, as directed by a healthcare professional. Your doctor will decide the exact dose and duration based on your white blood cell count and response to treatment. Never adjust or stop the dose on your own.


    Safety Advice For Neukine 300mcg Injection

    Breast Feeding

    Breast Feeding

    Unsafe

    Use with caution. It is not known if the medicine passes into breast milk. Consult your doctor before breastfeeding.

    Breast Feeding

    Alcohol

    Consult Your Doctor

    No specific interaction is known, but it is best to avoid or limit alcohol to prevent additional strain on the body during treatment.

    Breast Feeding

    Lungs

    Consult Your Doctor

    Use with caution if you have lung problems. Report symptoms like cough, chest pain, or breathing difficulty immediately.

    Breast Feeding

    Driving

    Unsafe

    Avoid driving if you feel dizzy, tired, or unwell after the injection.

    Breast Feeding

    Pregnancy

    Safe

    Use only if clearly needed. Inform your doctor if you are pregnant or planning to conceive.

    Storage Advice

  • Store in a refrigerator (2 - 8°C)
  • Do not freeze
  • Keep out of reach of children and pets

  • FAQs about Neukine 300mcg Injection

    Q1. What is Neukine 300mcg Injection used for?

    It is used to increase white blood cell count, reduce infection risk during chemotherapy, treat severe chronic neutropenia, support bone marrow recovery, and prepare stem cells for leukapheresis.

    Q2. How does Neukine work?

    Neukine contains filgrastim, which stimulates the bone marrow to produce more neutrophils, a type of white blood cell that helps fight infections.

    Q3. How is Neukine given?

    It is administered as an injection under the skin (subcutaneous) or into a vein (IV) by a healthcare professional.

    Q4. What are the common side effects of Neukine ?

    Common side effects include fever, bone or muscle pain, headache, rash, cough, fatigue, nausea, and injection site reactions.

    Q5. Can I use Neukine during pregnancy or breastfeeding?

    It should be used during pregnancy only if clearly needed, and breastfeeding should be done only after consulting your doctor.

    Q6. Who should avoid using Neukine?

    People with a history of severe allergic reactions to filgrastim or other serious health issues like spleen problems should avoid this injection, and patients should always inform their doctor of existing medical conditions.

    Key Fact Box

    Active ingredient Filgrastim
    Pharmacologic class colony-stimulating factor
    Medication category Hematopoietic
    Dosage forms Injection

    Medical Advisory

      The information on the Phoenix Pharmex website is shared for educational purposes only and is not a substitute for professional medical advice or treatment. Always consult a doctor for any health-related questions. Please avoid self diagnosis or delaying medical care based on this content. Our mission is to support informed decisions not replace professional medical guidance.

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