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Kadcyla 100mg Injection

Prescription Required
prescription
Cold Chain
cold chain

Manufacturer

ROCHE PRODUCTS INDIA PVT LTD

Origin of Medicine

Switzerland

₹128972.00

Inclusive of all taxes

Save ₹ 32243.31 (20%)
MRP:₹161215.31

₹128972.00

    MRP:₹161215.31
Save ₹ 32243.31 (20%)
1 Vial(s)

1 Vial(s)

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Overview & Usage

Overview

Kadcyla 100 mg Injection is a prescription cancer medicine that contains ado-trastuzumab emtansine. It is used to treat HER2-positive breast cancer that has either spread to other parts of the body or has not responded well to earlier treatments. Kadcyla combines two medicines in one: trastuzumab, which targets the HER2 protein on cancer cells, and emtansine, a chemotherapy drug that helps destroy those cells from the inside.

This medicine is used in both early and advanced stages of breast cancer, including cases where the cancer comes back within six months of completing chemotherapy. Kadcyla works specifically against tumors that produce higher-than-normal levels of the HER2 protein, helping slow down cancer growth and improve treatment outcomes.

Some patients may still have cancer remaining after chemotherapy and HER2-targeted treatment, which can affect recovery. It’s important to tell your doctor right away if you notice symptoms such as allergic reactions or unusual bleeding. Kadcyla generally does not affect kidney function, though infusion-related reactions can rarely occur. Common side effects include nausea, vomiting, diarrhea, and hair loss, which are usually mild and manageable under medical care.


Usage

1. Treatment of HER2-positive breast cancer body

2. Used in metastatic breast cancer that has spread to other parts of the body

3. Used in early-stage breast cancer with residual disease after chemotherapy

4. Helps manage recurrent breast cancer occurring within 6 months of prior chemotherapy

Pharmacological Effects

Ado-trastuzumab emtansine works by targeting HER2-positive cancer cells and delivering chemotherapy directly inside them. This helps destroy cancer cells from within, slow tumor growth, and reduce tumor size while limiting damage to healthy cells.


Side Effects

Side Effects of Kadcyla 100 mg Injection

Like all medications, Kadcyla 100 mg Injection may cause side effects. However, not everyone will experience them.

Serious Side Effects (Seek immediate medical attention):

  • Liver problems (raised liver enzymes, jaundice)
  • Heart problems (reduced heart function, shortness of breath)
  • Low platelet count, leading to unusual bleeding or bruising
  • Severe allergic or infusion-related reactions
  • Lung problems (cough, difficulty breathing)
  • Nerve damage causing numbness or tingling in hands and feet
  • Note: Always consult your doctor if you experience any unusual symptoms or if common side effects become severe.

Common Side Effects (Usually mild and temporary):

    These are usually mild to moderate and may improve as your body adjusts to the treatment:

  • Nausea or vomiting
  • Fatigue or tiredness
  • Diarrhea or constipation
  • Headache
  • Muscle or joint pain
  • Hair thinning or hair loss
  • Mouth sores
  • Decreased appetite

Dosage

Kadcyla 100 mg Injection is given as an intravenous infusion by a trained healthcare professional in a hospital or clinic. The dosage is based on the patient’s body weight, overall health, and response to treatment, and it is usually administered once every three weeks. Your doctor may adjust the dose or delay treatment depending on side effects, so it is important to follow the prescribed treatment schedule closely.


Safety Advice for Kadcyla 100 mg Injection

Breast Feeding

Breast Feeding

Unsafe

Breastfeeding is not recommended during treatment with Kadcyla and for at least 7 months after the final dose, as the medicine may pass into breast milk and harm the baby.

Breast Feeding

Alcohol

Consult Your Doctor

Alcohol should be consumed with caution during treatment, as Kadcyla can affect liver function and alcohol may increase the risk of liver-related side effects. It is best to consult your doctor before drinking alcohol.

Breast Feeding

Lungs

Unsafe

Kadcyla may rarely cause lung-related problems such as inflammation or breathing difficulty. Inform your doctor immediately if you experience persistent cough, shortness of breath, or chest discomfort.

Breast Feeding

Driving

Unsafe

Kadcyla can cause fatigue, dizziness, or weakness in some patients. Avoid driving or operating heavy machinery if you do not feel fully alert after receiving the injection.

Breast Feeding

Pregnancy

Unsafe

Kadcyla should not be used during pregnancy as it may harm the unborn baby. Women of childbearing potential should use effective contraception during treatment and for several months after the last dose, as advised by the doctor.

Storage Advice

  • Store in a refrigerator (2 - 8°C)
  • Do not freeze
  • Keep out of reach of children and pets

  • FAQs about Kadcyla 160 mg Injection

    Q1. What is Kadcyla 100 mg Injection used for?

    Kadcyla is used to treat HER2-positive breast cancer, including early-stage disease with residual cancer and advanced or metastatic breast cancer.

    Q2. How does Kadcyla work?

    Kadcyla targets HER2-positive cancer cells and delivers chemotherapy directly inside them, helping destroy cancer cells while limiting damage to healthy tissue.

    Q3. How is Kadcyla given?

    It is given as an intravenous (IV) infusion by a healthcare professional, usually once every 3 weeks.

    Q4. What are the common side effects of Kadcyla?

    Common side effects include nausea, fatigue, diarrhea, hair thinning, muscle or joint pain, and low platelet counts.

    Q5. Is Kadcyla safe during pregnancy or breastfeeding?

    No. Kadcyla can harm an unborn baby and should not be used during pregnancy. Breastfeeding should be avoided during treatment and for several months after the last dose.

    Q6. What monitoring is required during Kadcyla treatment?

    Regular tests are needed to monitor heart function, liver health, and blood counts throughout treatment.

    Key Fact Box

    Active ingredient Ado-Trastuzumab Emtansine
    Pharmacologic class HER2 inhibitor
    Medication category ANTI NEOPLASTICS
    Dosage forms Injection

    Medical Advisory

      The information on the Phoenix Pharmex website is shared for educational purposes only and is not a substitute for professional medical advice or treatment. Always consult a doctor for any health-related questions. Please avoid self diagnosis or delaying medical care based on this content. Our mission is to support informed decisions not replace professional medical guidance.

    DOSAGE

    Frequently Asked Questions

    Azadine 100mg Injection contains Azacitidine which belongs to the group of medicines called Anticancer agents. It is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Azadine 100mg Injection is typically used in adults who cannot undergo stem cell transplantation. It may be also used to treat other conditions, as determined by the doctor.

    Azadine Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised.

    You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.

    Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.

    MEDICINAL USE OF AZADINE 100MG INJECTION

    Azadine 100mg Injection is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    It is used to treat:

    • All sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow)
    • Chronic myelomonocytic leukemia (CMML; blood cancer of monocytes)
    • Acute myeloid leukemia (AML; blood cancer of WBC)
    SIDE EFFECTS OF AZADINE 100MG INJECTION

    Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

    • Low RBC count causing anemia, tiredness and pale skin
    • Increased infections, lung infections (pneumonia), fever and chills
    • Increased bleeding tendency due to low blood platelet counts
    • Nausea, vomiting
    • Diarrhea, constipation, loss of appetite, stomach pain
    • Tiredness, weakness
    • Injection site reactions (such as pain, redness and swelling or lump formation)
    • Joint pain, muscle pain, skin rashes with redness and itching
    • Sore nose and throat, cold sores, sinnusitis
    • Headache, dizziness
    • Trouble sleeping (insomnia)
    • Nosebleeds, bleeding gums
    • Weight loss
    • Urinary tract infections
    • Ulcers of mouth or tongue
    • High or low blood pressure
    • Anxiety, confusion
    • Hair loss, dehydration
    • Oral fungal infection
    • Sleepiness
    • Fluid around the lungs or heart
    DOSAGE OF AZADINE 100MG INJECTION
    • The dose of Azacitidine is determined by the patient's height, weight, and general condition. It is given under the skin of your thigh, stomach, or upper arm.
    • Minimum of 4 to 6 cycles; may continue treatment if the patient continues to benefit.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified health care professional, the likelihood of a missed dose is very low.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

    Ques 1: What is the use of AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Ques 2: How does AZADINE 100MG INJECTION works?

    Ans :AZADINE 100MG INJECTION is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    Ques 3: Can I take AZADINE 100MG INJECTION during breastfeeding?

    Ans :No. AZADINE 100MG INJECTION is not recommended for use in breast-feeding women. Therefore, inform your doctor before receiving it.

    Ques 4: Can AZADINE 100MG INJECTION increase the risk of infections?

    Ans :AZADINE 100MG INJECTION may cause a drop in the number of white blood cells in the body and may weaken your immune system. As a result, you may be at a greater risk of getting infected while receiving AZADINE 100MG INJECTION. To avoid this, your doctor will regular monitor your blood counts as a precaution. However, inform your doctor if you experience any signs of infection such as fever.

    Ques 5: Can the use of AZADINE 100MG INJECTION make me feel tired?

    Ans :Yes. AZADINE 100MG INJECTION may make you feel tired easily. This is because, it reduces the levels of red blood cells in your blood and may make you anemic. Consult your doctor if you experience tiredness after receiving AZADINE 100MG INJECTION. Tiredness can also occur if you have any pre-existing disease conditions such as liver or kidney impairment while receiving this medicine.

    Ques 6: Can I drive a car after receiving AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION may make you feel tired or weak. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by AZADINE 100MG INJECTION.

    Ques 7: How AZADINE 100MG INJECTION is administered?

    Ans :AZADINE 100MG INJECTION will be given to you only by a doctor or a nurse beneath the skin (subcutaneously) of thighs, arms or abdomen.

    Ques 8: How to control nausea caused due to AZADINE 100MG INJECTION?

    Ans :Generally, anticancer medicines are associated with uncontrollable nausea and vomiting. To avoid this, your doctor would prescribe a suitable medicine to control them along with AZADINE 100MG INJECTION. If not, consult your doctor for a suitable anti-emetic medicine. Do not self-treat nausea.

    Overview

    Kadcyla 100 mg Injection is a prescription cancer medicine that contains ado-trastuzumab emtansine. It is used to treat HER2-positive breast cancer that has either spread to other parts of the body or has not responded well to earlier treatments. Kadcyla combines two medicines in one: trastuzumab, which targets the HER2 protein on cancer cells, and emtansine, a chemotherapy drug that helps destroy those cells from the inside.

    This medicine is used in both early and advanced stages of breast cancer, including cases where the cancer comes back within six months of completing chemotherapy. Kadcyla works specifically against tumors that produce higher-than-normal levels of the HER2 protein, helping slow down cancer growth and improve treatment outcomes.

    Some patients may still have cancer remaining after chemotherapy and HER2-targeted treatment, which can affect recovery. It’s important to tell your doctor right away if you notice symptoms such as allergic reactions or unusual bleeding. Kadcyla generally does not affect kidney function, though infusion-related reactions can rarely occur. Common side effects include nausea, vomiting, diarrhea, and hair loss, which are usually mild and manageable under medical care.


    Usage

    1. Treatment of HER2-positive breast cancer body

    2. Used in metastatic breast cancer that has spread to other parts of the body

    3. Used in early-stage breast cancer with residual disease after chemotherapy

    4. Helps manage recurrent breast cancer occurring within 6 months of prior chemotherapy

    Pharmacological Effects

    Ado-trastuzumab emtansine works by targeting HER2-positive cancer cells and delivering chemotherapy directly inside them. This helps destroy cancer cells from within, slow tumor growth, and reduce tumor size while limiting damage to healthy cells.


    Side Effects

    Side Effects of Kadcyla 100 mg Injection

    Like all medications, Kadcyla 100 mg Injection may cause side effects. However, not everyone will experience them.

    Serious Side Effects (Seek immediate medical attention):

    • Liver problems (raised liver enzymes, jaundice)
    • Heart problems (reduced heart function, shortness of breath)
    • Low platelet count, leading to unusual bleeding or bruising
    • Severe allergic or infusion-related reactions
    • Lung problems (cough, difficulty breathing)
    • Nerve damage causing numbness or tingling in hands and feet
    • Note: Always consult your doctor if you experience any unusual symptoms or if common side effects become severe.

    Common Side Effects (Usually mild and temporary):

      These are usually mild to moderate and may improve as your body adjusts to the treatment:

    • Nausea or vomiting
    • Fatigue or tiredness
    • Diarrhea or constipation
    • Headache
    • Muscle or joint pain
    • Hair thinning or hair loss
    • Mouth sores
    • Decreased appetite

    Dosage

    Kadcyla 100 mg Injection is given as an intravenous infusion by a trained healthcare professional in a hospital or clinic. The dosage is based on the patient’s body weight, overall health, and response to treatment, and it is usually administered once every three weeks. Your doctor may adjust the dose or delay treatment depending on side effects, so it is important to follow the prescribed treatment schedule closely.


    Safety Advice for Kadcyla 100 mg Injection

    Breast Feeding

    Breast Feeding

    Unsafe

    Breastfeeding is not recommended during treatment with Kadcyla and for at least 7 months after the final dose, as the medicine may pass into breast milk and harm the baby.

    Breast Feeding

    Alcohol

    Consult Your Doctor

    Alcohol should be consumed with caution during treatment, as Kadcyla can affect liver function and alcohol may increase the risk of liver-related side effects. It is best to consult your doctor before drinking alcohol.

    Breast Feeding

    Lungs

    Unsafe

    Kadcyla may rarely cause lung-related problems such as inflammation or breathing difficulty. Inform your doctor immediately if you experience persistent cough, shortness of breath, or chest discomfort.

    Breast Feeding

    Driving

    Unsafe

    Kadcyla can cause fatigue, dizziness, or weakness in some patients. Avoid driving or operating heavy machinery if you do not feel fully alert after receiving the injection.

    Breast Feeding

    Pregnancy

    Unsafe

    Kadcyla should not be used during pregnancy as it may harm the unborn baby. Women of childbearing potential should use effective contraception during treatment and for several months after the last dose, as advised by the doctor.

    Storage Advice

  • Store in a refrigerator (2 - 8°C)
  • Do not freeze
  • Keep out of reach of children and pets

  • FAQs about Kadcyla 160 mg Injection

    Q1. What is Kadcyla 100 mg Injection used for?

    Kadcyla is used to treat HER2-positive breast cancer, including early-stage disease with residual cancer and advanced or metastatic breast cancer.

    Q2. How does Kadcyla work?

    Kadcyla targets HER2-positive cancer cells and delivers chemotherapy directly inside them, helping destroy cancer cells while limiting damage to healthy tissue.

    Q3. How is Kadcyla given?

    It is given as an intravenous (IV) infusion by a healthcare professional, usually once every 3 weeks.

    Q4. What are the common side effects of Kadcyla?

    Common side effects include nausea, fatigue, diarrhea, hair thinning, muscle or joint pain, and low platelet counts.

    Q5. Is Kadcyla safe during pregnancy or breastfeeding?

    No. Kadcyla can harm an unborn baby and should not be used during pregnancy. Breastfeeding should be avoided during treatment and for several months after the last dose.

    Q6. What monitoring is required during Kadcyla treatment?

    Regular tests are needed to monitor heart function, liver health, and blood counts throughout treatment.

    Key Fact Box

    Active ingredient Ado-Trastuzumab Emtansine
    Pharmacologic class HER2 inhibitor
    Medication category ANTI NEOPLASTICS
    Dosage forms Injection

    Medical Advisory

      The information on the Phoenix Pharmex website is shared for educational purposes only and is not a substitute for professional medical advice or treatment. Always consult a doctor for any health-related questions. Please avoid self diagnosis or delaying medical care based on this content. Our mission is to support informed decisions not replace professional medical guidance.

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