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Isentress 400mg Tablet

Prescription Required
prescription

Salt Composition

Manufacturer

MSD PHARMACEUTICALS PVT LTD

Origin of Medicine

India

₹7000.00

Inclusive of all taxes

Save ₹ 1145.94 (14%)
MRP:₹8145.94

₹7000.00

    MRP:₹8145.94
Save ₹ 1145.94 (14%)
60 Tablet(s) In A Bottle

60 Tablet(s) In A Bottle

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Overview & Usage

Overview

Isentress 400mg Tablet is an antiretroviral medication used in the treatment of Human Immunodeficiency Virus (HIV) infection. It contains raltegravir as the active ingredient, which belongs to a class of drugs known as integrase strand transfer inhibitors (INSTIs). By inhibiting the integrase enzyme, Isentress prevents the virus from integrating its genetic material into human cells, thereby limiting the spread of HIV within the body.

Prescribed as part of combination antiretroviral therapy (ART), Isentress plays a vital role in helping to control viral replication, improve immune function, and reduce the risk of HIV-related complications. While it is not a cure for HIV or AIDS, consistent use of this medication, alongside other prescribed treatments and lifestyle adjustments, can significantly enhance the quality of life for individuals living with HIV.

Before starting this medication, inform your doctor if you have any liver, kidney, or skin conditions. You may need regular blood tests to check liver function and blood counts while on this treatment. Avoid alcohol, as it can increase the risk of liver damage. If you are pregnant or breastfeeding, consult your doctor before use. To reduce the risk of transmitting HIV, avoid sharing personal items like razors or toothbrushes, and practice safe sex using condoms.

Common side effects of Isentress 400mg Tablet may include insomnia (trouble sleeping), headache, nausea, dizziness, and muscle pain. These effects are generally mild and temporary, but inform your doctor if they persist or become bothersome. In rare cases, serious side effects such as skin reactions or liver problems may occur. Your doctor will monitor you closely, especially during the early stages of treatment.


Usage

1. Treatment of HIV Infection:

Isentress 400mg Tablet, used with other antiretrovirals, helps reduce the viral load, improve immune function, and lower the risk of HIV-related complications.

2. Prevention of HIV Progression:

By suppressing the virus, it helps prevent HIV from progressing to AIDS and reduces the chance of serious infections.

Pharmacological Effects

Isentress 400mg Tablet contains raltegravir, an antiretroviral drug that belongs to the class of integrase strand transfer inhibitors (INSTIs). It works by inhibiting the HIV integrase enzyme, which is essential for the virus to replicate.

During HIV replication, the virus needs to insert its genetic material into the DNA of human cells. The integrase enzyme performs this critical step. Raltegravir blocks this process, thereby preventing the integration of viral DNA into the host cell's genome. As a result, it stops the virus from multiplying and helps reduce the viral load in the body.


Side Effects

Side Effects of Isentress 400mg Tablet

Like all medications, Isentress 400mg Tablet may cause side effects. However, not everyone will experience them.

Serious Side Effects (Seek immediate medical attention):

  • Severe liver problems
  • Serious allergic reactions (rash, swelling, breathing trouble)
  • Depression or mood changes
  • Low white blood cell count (neutropenia), increasing infection risk
  • Breakdown of muscle tissue (rhabdomyolysis)
  • High levels of creatine kinase (may indicate muscle damage)
  • Note: Always consult your doctor if you experience any unusual symptoms or if common side effects become severe.

Common Side Effects (Usually mild and temporary):

    These are usually mild to moderate and may improve as your body adjusts to the treatment:

  • Nausea or vomiting
  • Fatigue or tiredness
  • Insomnia (difficulty sleeping)
  • Diarrhea or constipation
  • Headache
  • Muscle or joint pain
  • Skin rash or itching
  • Infusion-related reactions (fever, chills, or flushing)
  • Decreased appetite

Dosage

The recommended dose of Isentress 400mg Tablet is one tablet taken twice daily, with or without food. It should be swallowed whole with a glass of water at the same time each day to maintain steady drug levels. Always follow your doctor’s dosage instructions and avoid skipping or altering the dose without medical guidance.


Safety Advice for Isentress 400mg Tablet

Breast Feeding

Breast Feeding

Unsafe

Avoid breastfeeding while taking this medicine, as HIV can be transmitted through breast milk.

Breast Feeding

Alcohol

Consult Your Doctor

Avoid consuming alcohol while taking Isentress, as it may increase the risk of liver damage.

Breast Feeding

Liver

Unsafe

Use with caution in patients with liver disorders. Regular monitoring may be required.

Breast Feeding

Driving

Unsafe

Dizziness or fatigue may occur. Avoid driving or operating heavy machinery if you feel unwell.

Breast Feeding

Pregnancy

Unsafe

Use only if prescribed by a doctor. Inform your doctor if you are pregnant or planning to become pregnant.

Storage Advice

  • Store at room temperature between 20°C to 25°
  • Keep out of reach of children and pets
  • Keep the tablets in the original packaging to protect them from moisture and light

  • FAQs about Isentress 400mg Tablet

    Q1. What is Isentress 400mg Tablet used for?

    Isentress 400mg Tablet is used in combination with other antiretroviral medicines to treat HIV infection. It helps reduce the viral load and improve immune function.

    Q2. Can Isentress cure HIV/AIDS?

    No, Isentress does not cure HIV or AIDS. It helps manage the infection by reducing the amount of virus in the body and preventing disease progression.

    Q3. How should I take Isentress 400mg Tablet?

    It should be taken exactly as prescribed by your doctor, usually 400 mg twice daily, with or without food.

    Q4. What should I do if I miss a dose?

    Take the missed dose as soon as you remember. If it’s almost time for the next dose, skip the missed one. Do not double the dose to make up for a missed dose.

    Q5. Can I take Isentress with other medications?

    Always inform your doctor about all medications, supplements, or herbal products you are using. Some drugs may interact with Isentress and affect its effectiveness or increase side effects.

    Q6. What are the common side effects of Isentress?

    Common side effects include headache, nausea, insomnia, dizziness, and muscle pain. Serious side effects are rare but may include liver problems or severe skin reactions.

    Q7. Is Isentress safe during pregnancy or breastfeeding?

    Inform your doctor if you are pregnant or planning to become pregnant. Breastfeeding is not recommended, as HIV can be passed through breast milk.

    Q8. Can I drink alcohol while taking Isentress?

    It is best to avoid alcohol, as it may increase the risk of liver damage while taking this medicine.

    Key Fact Box

    Active ingredient Raltegravir
    Pharmacologic class Antiretroviral Agent – Integrase Strand Transfer Inhibitor (INSTI)
    Medication category Antiretroviral
    Dosage forms Tablet

    Medical Advisory

      The information on the Phoenix Pharmex website is shared for educational purposes only and is not a substitute for professional medical advice or treatment. Always consult a doctor for any health-related questions. Please avoid self diagnosis or delaying medical care based on this content. Our mission is to support informed decisions not replace professional medical guidance.

    DOSAGE

    Frequently Asked Questions

    Azadine 100mg Injection contains Azacitidine which belongs to the group of medicines called Anticancer agents. It is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Azadine 100mg Injection is typically used in adults who cannot undergo stem cell transplantation. It may be also used to treat other conditions, as determined by the doctor.

    Azadine Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised.

    You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.

    Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.

    MEDICINAL USE OF AZADINE 100MG INJECTION

    Azadine 100mg Injection is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    It is used to treat:

    • All sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow)
    • Chronic myelomonocytic leukemia (CMML; blood cancer of monocytes)
    • Acute myeloid leukemia (AML; blood cancer of WBC)
    SIDE EFFECTS OF AZADINE 100MG INJECTION

    Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

    • Low RBC count causing anemia, tiredness and pale skin
    • Increased infections, lung infections (pneumonia), fever and chills
    • Increased bleeding tendency due to low blood platelet counts
    • Nausea, vomiting
    • Diarrhea, constipation, loss of appetite, stomach pain
    • Tiredness, weakness
    • Injection site reactions (such as pain, redness and swelling or lump formation)
    • Joint pain, muscle pain, skin rashes with redness and itching
    • Sore nose and throat, cold sores, sinnusitis
    • Headache, dizziness
    • Trouble sleeping (insomnia)
    • Nosebleeds, bleeding gums
    • Weight loss
    • Urinary tract infections
    • Ulcers of mouth or tongue
    • High or low blood pressure
    • Anxiety, confusion
    • Hair loss, dehydration
    • Oral fungal infection
    • Sleepiness
    • Fluid around the lungs or heart
    DOSAGE OF AZADINE 100MG INJECTION
    • The dose of Azacitidine is determined by the patient's height, weight, and general condition. It is given under the skin of your thigh, stomach, or upper arm.
    • Minimum of 4 to 6 cycles; may continue treatment if the patient continues to benefit.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified health care professional, the likelihood of a missed dose is very low.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

    Ques 1: What is the use of AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Ques 2: How does AZADINE 100MG INJECTION works?

    Ans :AZADINE 100MG INJECTION is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    Ques 3: Can I take AZADINE 100MG INJECTION during breastfeeding?

    Ans :No. AZADINE 100MG INJECTION is not recommended for use in breast-feeding women. Therefore, inform your doctor before receiving it.

    Ques 4: Can AZADINE 100MG INJECTION increase the risk of infections?

    Ans :AZADINE 100MG INJECTION may cause a drop in the number of white blood cells in the body and may weaken your immune system. As a result, you may be at a greater risk of getting infected while receiving AZADINE 100MG INJECTION. To avoid this, your doctor will regular monitor your blood counts as a precaution. However, inform your doctor if you experience any signs of infection such as fever.

    Ques 5: Can the use of AZADINE 100MG INJECTION make me feel tired?

    Ans :Yes. AZADINE 100MG INJECTION may make you feel tired easily. This is because, it reduces the levels of red blood cells in your blood and may make you anemic. Consult your doctor if you experience tiredness after receiving AZADINE 100MG INJECTION. Tiredness can also occur if you have any pre-existing disease conditions such as liver or kidney impairment while receiving this medicine.

    Ques 6: Can I drive a car after receiving AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION may make you feel tired or weak. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by AZADINE 100MG INJECTION.

    Ques 7: How AZADINE 100MG INJECTION is administered?

    Ans :AZADINE 100MG INJECTION will be given to you only by a doctor or a nurse beneath the skin (subcutaneously) of thighs, arms or abdomen.

    Ques 8: How to control nausea caused due to AZADINE 100MG INJECTION?

    Ans :Generally, anticancer medicines are associated with uncontrollable nausea and vomiting. To avoid this, your doctor would prescribe a suitable medicine to control them along with AZADINE 100MG INJECTION. If not, consult your doctor for a suitable anti-emetic medicine. Do not self-treat nausea.

    Overview

    Isentress 400mg Tablet is an antiretroviral medication used in the treatment of Human Immunodeficiency Virus (HIV) infection. It contains raltegravir as the active ingredient, which belongs to a class of drugs known as integrase strand transfer inhibitors (INSTIs). By inhibiting the integrase enzyme, Isentress prevents the virus from integrating its genetic material into human cells, thereby limiting the spread of HIV within the body.

    Prescribed as part of combination antiretroviral therapy (ART), Isentress plays a vital role in helping to control viral replication, improve immune function, and reduce the risk of HIV-related complications. While it is not a cure for HIV or AIDS, consistent use of this medication, alongside other prescribed treatments and lifestyle adjustments, can significantly enhance the quality of life for individuals living with HIV.

    Before starting this medication, inform your doctor if you have any liver, kidney, or skin conditions. You may need regular blood tests to check liver function and blood counts while on this treatment. Avoid alcohol, as it can increase the risk of liver damage. If you are pregnant or breastfeeding, consult your doctor before use. To reduce the risk of transmitting HIV, avoid sharing personal items like razors or toothbrushes, and practice safe sex using condoms.

    Common side effects of Isentress 400mg Tablet may include insomnia (trouble sleeping), headache, nausea, dizziness, and muscle pain. These effects are generally mild and temporary, but inform your doctor if they persist or become bothersome. In rare cases, serious side effects such as skin reactions or liver problems may occur. Your doctor will monitor you closely, especially during the early stages of treatment.


    Usage

    1. Treatment of HIV Infection:

    Isentress 400mg Tablet, used with other antiretrovirals, helps reduce the viral load, improve immune function, and lower the risk of HIV-related complications.

    2. Prevention of HIV Progression:

    By suppressing the virus, it helps prevent HIV from progressing to AIDS and reduces the chance of serious infections.

    Pharmacological Effects

    Isentress 400mg Tablet contains raltegravir, an antiretroviral drug that belongs to the class of integrase strand transfer inhibitors (INSTIs). It works by inhibiting the HIV integrase enzyme, which is essential for the virus to replicate.

    During HIV replication, the virus needs to insert its genetic material into the DNA of human cells. The integrase enzyme performs this critical step. Raltegravir blocks this process, thereby preventing the integration of viral DNA into the host cell's genome. As a result, it stops the virus from multiplying and helps reduce the viral load in the body.


    Side Effects

    Side Effects of Isentress 400mg Tablet

    Like all medications, Isentress 400mg Tablet may cause side effects. However, not everyone will experience them.

    Serious Side Effects (Seek immediate medical attention):

    • Severe liver problems
    • Serious allergic reactions (rash, swelling, breathing trouble)
    • Depression or mood changes
    • Low white blood cell count (neutropenia), increasing infection risk
    • Breakdown of muscle tissue (rhabdomyolysis)
    • High levels of creatine kinase (may indicate muscle damage)
    • Note: Always consult your doctor if you experience any unusual symptoms or if common side effects become severe.

    Common Side Effects (Usually mild and temporary):

      These are usually mild to moderate and may improve as your body adjusts to the treatment:

    • Nausea or vomiting
    • Fatigue or tiredness
    • Insomnia (difficulty sleeping)
    • Diarrhea or constipation
    • Headache
    • Muscle or joint pain
    • Skin rash or itching
    • Infusion-related reactions (fever, chills, or flushing)
    • Decreased appetite

    Dosage

    The recommended dose of Isentress 400mg Tablet is one tablet taken twice daily, with or without food. It should be swallowed whole with a glass of water at the same time each day to maintain steady drug levels. Always follow your doctor’s dosage instructions and avoid skipping or altering the dose without medical guidance.


    Safety Advice for Isentress 400mg Tablet

    Breast Feeding

    Breast Feeding

    Unsafe

    Avoid breastfeeding while taking this medicine, as HIV can be transmitted through breast milk.

    Breast Feeding

    Alcohol

    Consult Your Doctor

    Avoid consuming alcohol while taking Isentress, as it may increase the risk of liver damage.

    Breast Feeding

    Liver

    Unsafe

    Use with caution in patients with liver disorders. Regular monitoring may be required.

    Breast Feeding

    Driving

    Unsafe

    Dizziness or fatigue may occur. Avoid driving or operating heavy machinery if you feel unwell.

    Breast Feeding

    Pregnancy

    Unsafe

    Use only if prescribed by a doctor. Inform your doctor if you are pregnant or planning to become pregnant.

    Storage Advice

  • Store at room temperature between 20°C to 25°
  • Keep out of reach of children and pets
  • Keep the tablets in the original packaging to protect them from moisture and light

  • FAQs about Isentress 400mg Tablet

    Q1. What is Isentress 400mg Tablet used for?

    Isentress 400mg Tablet is used in combination with other antiretroviral medicines to treat HIV infection. It helps reduce the viral load and improve immune function.

    Q2. Can Isentress cure HIV/AIDS?

    No, Isentress does not cure HIV or AIDS. It helps manage the infection by reducing the amount of virus in the body and preventing disease progression.

    Q3. How should I take Isentress 400mg Tablet?

    It should be taken exactly as prescribed by your doctor, usually 400 mg twice daily, with or without food.

    Q4. What should I do if I miss a dose?

    Take the missed dose as soon as you remember. If it’s almost time for the next dose, skip the missed one. Do not double the dose to make up for a missed dose.

    Q5. Can I take Isentress with other medications?

    Always inform your doctor about all medications, supplements, or herbal products you are using. Some drugs may interact with Isentress and affect its effectiveness or increase side effects.

    Q6. What are the common side effects of Isentress?

    Common side effects include headache, nausea, insomnia, dizziness, and muscle pain. Serious side effects are rare but may include liver problems or severe skin reactions.

    Q7. Is Isentress safe during pregnancy or breastfeeding?

    Inform your doctor if you are pregnant or planning to become pregnant. Breastfeeding is not recommended, as HIV can be passed through breast milk.

    Q8. Can I drink alcohol while taking Isentress?

    It is best to avoid alcohol, as it may increase the risk of liver damage while taking this medicine.

    Key Fact Box

    Active ingredient Raltegravir
    Pharmacologic class Antiretroviral Agent – Integrase Strand Transfer Inhibitor (INSTI)
    Medication category Antiretroviral
    Dosage forms Tablet

    Medical Advisory

      The information on the Phoenix Pharmex website is shared for educational purposes only and is not a substitute for professional medical advice or treatment. Always consult a doctor for any health-related questions. Please avoid self diagnosis or delaying medical care based on this content. Our mission is to support informed decisions not replace professional medical guidance.

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