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Ujvira 160mg Injection

prescription

Salt Composition

TRASTUZUMAB EMTANSINE

Manufacturer

ZYDUS CADILA

Origin of Medicine

India

₹31000.00

Inclusive of all taxes

Save ₹ 25992 (46%)
MRP:₹56992.00

₹31000.00

    MRP:₹56992.00
Save ₹ 25992 (46%)
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1 Vial(s)

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Overview & Usage

Overview

Ujvira 160 mg Injection contains Trastuzumab Emtansine, an advanced cancer medicine from the Antibody-Drug Conjugates (ADCs) group. It combines a targeted monoclonal antibody with chemotherapy, helping attack cancer cells more precisely while reducing damage to healthy tissues.

It is mainly used for treating HER2-positive metastatic breast cancer, including relapsed or recurrent cases where cure may not be possible. By binding to HER2 receptors on cancer cells, Ujvira delivers chemotherapy directly inside the cell, disrupting its growth and survival. This targeted action makes the treatment more effective and safer for surrounding healthy cells.

Ujvira is given intravenously by a doctor in a hospital setting. The dose and duration depend on individual health needs and treatment response. Common side effects include nausea, mouth sores, rashes, numbness in hands or feet, joint pain, hair loss, and urinary infections. Patients should inform their doctor if side effects become severe.


Usage

1. Treatment of HER2-positive metastatic breast cancer

Ujvira is used to treat breast cancer that has spread beyond the breast to other parts of the body (metastatic) and shows overexpression of the HER2 protein.

2. Management of locally advanced or unresectable breast cancer

It is used when the cancer cannot be completely removed by surgery and is HER2-positive.

3. For patients previously treated with trastuzumab and a taxane

Ujvira is specifically indicated for patients who have already received prior therapy including trastuzumab and taxane-based chemotherapy.

4. Treatment of relapsed or recurrent breast cancer

It may be used when breast cancer has come back after initial treatment and is no longer responding to standard therapies.

Pharmacological Effects

Ujvira 160 mg Injection works in a smart and targeted way by combining two powerful actions. It uses trastuzumab to find and attach to HER2-positive breast cancer cells, then delivers the chemotherapy drug emtansine directly inside them. This allows the medicine to stop cancer cells from growing and destroy them from within, while reducing harm to healthy cells.


Side Effects

Side Effects of Ujvira 160 mg Injection

Like all medications, Ujvira 160 mg Injection may cause side effects. However, not everyone will experience them.

Serious Side Effects (Seek immediate medical attention):

  • Severe liver problems or liver failure
  • Serious allergic reactions (rash, swelling, breathing trouble)
  • Heart problems (such as reduced heart function or heart failure)
  • Signs of infection (fever, chills, sore throat)
  • Serious lung problems, including difficulty breathing or interstitial lung disease
  • Vision changes or eye irritation.
  • Note: Always consult your doctor if you experience any unusual symptoms or if common side effects become severe.

Common Side Effects (Usually mild and temporary):

    These are usually mild to moderate and may improve as your body adjusts to the treatment:

  • Nausea or vomiting
  • Fatigue or tiredness
  • Mouth sores or ulcers
  • Diarrhea or constipation
  • Headache
  • Muscle or joint pain
  • Hair thinning or hair loss
  • Skin rash or itching
  • Insomnia (difficulty sleeping)
  • Tingling or numbness in hands and feet (peripheral neuropathy)
  • Low red blood cell count (anemia)
  • Increased liver enzymes (seen in blood tests)

Dosage

The dosage of Ujvira 160 mg Injection is decided by your doctor based on your body weight, medical condition, and treatment response. It is given as an intravenous (IV) infusion in a hospital or clinic by a trained healthcare professional. Ujvira is usually given once every three weeks. Your doctor will adjust the dose or delay treatment if you experience certain side effects. It is very important to follow the treatment schedule exactly as prescribed and not to miss any doses.


Safety Advice for Ujvira 160 mg Injection

Breast Feeding

Breast Feeding

Unsafe

This medicine is not safe during breastfeeding as it may harm the baby. Avoid breastfeeding during treatment and for at least 7 months after the last dose.

Breast Feeding

Alcohol

Consult Your Doctor

It is best to avoid or limit alcohol while receiving Ujvira 160 mg Injection, as alcohol can increase side effects like liver problems, tiredness, or nausea. Always consult your doctor before drinking alcohol during treatment.

Breast Feeding

Lungs

Unsafe

Ujvira 160 mg Injection may sometimes affect the lungs, causing breathing problems like cough, shortness of breath, or chest discomfort. If you notice any new or worsening breathing issues, inform your doctor right away. Regular check-ups and early reporting of symptoms can help prevent serious lung complications during treatment.

Breast Feeding

Driving

Unsafe

Ujvira 160 mg Injection may cause side effects like tiredness, dizziness, or vision changes. If you feel unwell or experience these symptoms, avoid driving or operating heavy machines until you feel better. Always check with your doctor before resuming such activities.

Breast Feeding

Pregnancy

Unsafe

Ujvira 160 mg Injection is not safe to use during pregnancy, as it may harm the unborn baby. Women should use effective birth control during treatment and for a few months after the last dose. If you are pregnant, planning to conceive, or become pregnant while on this medicine, inform your doctor immediately.

Storage Advice

  • Store in a refrigerator (2 - 8°C)
  • Do not freeze
  • Keep out of reach of children and pets

  • FAQs about Ujvira 160 mg Injection

    Q1. What is Ujvira 160 mg Injection used for?

    Ujvira is used to treat HER2-positive metastatic breast cancer, especially in patients who have already received prior treatment with trastuzumab and chemotherapy.

    Q2. How is Ujvira 160 mg Injection given?

    It is given as an intravenous (IV) infusion by a trained healthcare provider, usually once every three weeks.

    Q3. Can I take Ujvira during pregnancy?

    No. Ujvira should not be used during pregnancy, as it may harm the unborn baby. Use effective contraception during treatment and for 7 months after the last dose.

    Q4. Is Ujvira safe during breastfeeding?

    No. Breastfeeding should be avoided during treatment and for at least 7 months after the final dose.

    Q5. What are the common side effects of Ujvira?

    Common side effects include nausea, fatigue, mouth sores, hair thinning, skin rash, and numbness in hands or feet. Serious side effects like heart or liver problems can also occur.

    Q6. Will I lose my hair during Ujvira treatment?

    Hair thinning or partial hair loss may occur, but complete hair loss is less common compared to traditional chemotherapy.

    Q7. Can Ujvira cause liver or heart problems?

    Yes. Ujvira can affect liver function and heart performance, so regular monitoring is required during treatment.

    Q8. How long will I need to take Ujvira?

    The duration depends on how well your body responds and your doctor’s recommendation. It is typically given in 3-week cycles until disease progression or unacceptable side effects.

    Q9. Can I drive after receiving Ujvira?

    If you feel dizzy or tired, it is best to avoid driving or operating machinery until you feel well again.

    Q10. Will I lose my hair during Ujvira treatment?What precautions should I take while on Ujvira?

    Use contraception, attend regular checkups, report any signs of infection, and inform your doctor about all other medications you're taking.

    Key Fact Box

    Active ingredient TRASTUZUMAB EMTANSINE
    Pharmacologic class Antibody-Drug Conjugates (ADCs)
    Medication category ANTI NEOPLASTICS
    Dosage forms Injection

    DOSAGE

    Frequently Asked Questions

    Azadine 100mg Injection contains Azacitidine which belongs to the group of medicines called Anticancer agents. It is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Azadine 100mg Injection is typically used in adults who cannot undergo stem cell transplantation. It may be also used to treat other conditions, as determined by the doctor.

    Azadine Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised.

    You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.

    Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.

    MEDICINAL USE OF AZADINE 100MG INJECTION

    Azadine 100mg Injection is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    It is used to treat:

    • All sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow)
    • Chronic myelomonocytic leukemia (CMML; blood cancer of monocytes)
    • Acute myeloid leukemia (AML; blood cancer of WBC)
    SIDE EFFECTS OF AZADINE 100MG INJECTION

    Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

    • Low RBC count causing anemia, tiredness and pale skin
    • Increased infections, lung infections (pneumonia), fever and chills
    • Increased bleeding tendency due to low blood platelet counts
    • Nausea, vomiting
    • Diarrhea, constipation, loss of appetite, stomach pain
    • Tiredness, weakness
    • Injection site reactions (such as pain, redness and swelling or lump formation)
    • Joint pain, muscle pain, skin rashes with redness and itching
    • Sore nose and throat, cold sores, sinnusitis
    • Headache, dizziness
    • Trouble sleeping (insomnia)
    • Nosebleeds, bleeding gums
    • Weight loss
    • Urinary tract infections
    • Ulcers of mouth or tongue
    • High or low blood pressure
    • Anxiety, confusion
    • Hair loss, dehydration
    • Oral fungal infection
    • Sleepiness
    • Fluid around the lungs or heart
    DOSAGE OF AZADINE 100MG INJECTION
    • The dose of Azacitidine is determined by the patient's height, weight, and general condition. It is given under the skin of your thigh, stomach, or upper arm.
    • Minimum of 4 to 6 cycles; may continue treatment if the patient continues to benefit.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified health care professional, the likelihood of a missed dose is very low.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

    Ques 1: What is the use of AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Ques 2: How does AZADINE 100MG INJECTION works?

    Ans :AZADINE 100MG INJECTION is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    Ques 3: Can I take AZADINE 100MG INJECTION during breastfeeding?

    Ans :No. AZADINE 100MG INJECTION is not recommended for use in breast-feeding women. Therefore, inform your doctor before receiving it.

    Ques 4: Can AZADINE 100MG INJECTION increase the risk of infections?

    Ans :AZADINE 100MG INJECTION may cause a drop in the number of white blood cells in the body and may weaken your immune system. As a result, you may be at a greater risk of getting infected while receiving AZADINE 100MG INJECTION. To avoid this, your doctor will regular monitor your blood counts as a precaution. However, inform your doctor if you experience any signs of infection such as fever.

    Ques 5: Can the use of AZADINE 100MG INJECTION make me feel tired?

    Ans :Yes. AZADINE 100MG INJECTION may make you feel tired easily. This is because, it reduces the levels of red blood cells in your blood and may make you anemic. Consult your doctor if you experience tiredness after receiving AZADINE 100MG INJECTION. Tiredness can also occur if you have any pre-existing disease conditions such as liver or kidney impairment while receiving this medicine.

    Ques 6: Can I drive a car after receiving AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION may make you feel tired or weak. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by AZADINE 100MG INJECTION.

    Ques 7: How AZADINE 100MG INJECTION is administered?

    Ans :AZADINE 100MG INJECTION will be given to you only by a doctor or a nurse beneath the skin (subcutaneously) of thighs, arms or abdomen.

    Ques 8: How to control nausea caused due to AZADINE 100MG INJECTION?

    Ans :Generally, anticancer medicines are associated with uncontrollable nausea and vomiting. To avoid this, your doctor would prescribe a suitable medicine to control them along with AZADINE 100MG INJECTION. If not, consult your doctor for a suitable anti-emetic medicine. Do not self-treat nausea.

    Overview

    Ujvira 160 mg Injection contains Trastuzumab Emtansine, an advanced cancer medicine from the Antibody-Drug Conjugates (ADCs) group. It combines a targeted monoclonal antibody with chemotherapy, helping attack cancer cells more precisely while reducing damage to healthy tissues.

    It is mainly used for treating HER2-positive metastatic breast cancer, including relapsed or recurrent cases where cure may not be possible. By binding to HER2 receptors on cancer cells, Ujvira delivers chemotherapy directly inside the cell, disrupting its growth and survival. This targeted action makes the treatment more effective and safer for surrounding healthy cells.

    Ujvira is given intravenously by a doctor in a hospital setting. The dose and duration depend on individual health needs and treatment response. Common side effects include nausea, mouth sores, rashes, numbness in hands or feet, joint pain, hair loss, and urinary infections. Patients should inform their doctor if side effects become severe.


    Usage

    1. Treatment of HER2-positive metastatic breast cancer

    Ujvira is used to treat breast cancer that has spread beyond the breast to other parts of the body (metastatic) and shows overexpression of the HER2 protein.

    2. Management of locally advanced or unresectable breast cancer

    It is used when the cancer cannot be completely removed by surgery and is HER2-positive.

    3. For patients previously treated with trastuzumab and a taxane

    Ujvira is specifically indicated for patients who have already received prior therapy including trastuzumab and taxane-based chemotherapy.

    4. Treatment of relapsed or recurrent breast cancer

    It may be used when breast cancer has come back after initial treatment and is no longer responding to standard therapies.

    Pharmacological Effects

    Ujvira 160 mg Injection works in a smart and targeted way by combining two powerful actions. It uses trastuzumab to find and attach to HER2-positive breast cancer cells, then delivers the chemotherapy drug emtansine directly inside them. This allows the medicine to stop cancer cells from growing and destroy them from within, while reducing harm to healthy cells.


    Side Effects

    Side Effects of Ujvira 160 mg Injection

    Like all medications, Ujvira 160 mg Injection may cause side effects. However, not everyone will experience them.

    Serious Side Effects (Seek immediate medical attention):

    • Severe liver problems or liver failure
    • Serious allergic reactions (rash, swelling, breathing trouble)
    • Heart problems (such as reduced heart function or heart failure)
    • Signs of infection (fever, chills, sore throat)
    • Serious lung problems, including difficulty breathing or interstitial lung disease
    • Vision changes or eye irritation.
    • Note: Always consult your doctor if you experience any unusual symptoms or if common side effects become severe.

    Common Side Effects (Usually mild and temporary):

      These are usually mild to moderate and may improve as your body adjusts to the treatment:

    • Nausea or vomiting
    • Fatigue or tiredness
    • Mouth sores or ulcers
    • Diarrhea or constipation
    • Headache
    • Muscle or joint pain
    • Hair thinning or hair loss
    • Skin rash or itching
    • Insomnia (difficulty sleeping)
    • Tingling or numbness in hands and feet (peripheral neuropathy)
    • Low red blood cell count (anemia)
    • Increased liver enzymes (seen in blood tests)

    Dosage

    The dosage of Ujvira 160 mg Injection is decided by your doctor based on your body weight, medical condition, and treatment response. It is given as an intravenous (IV) infusion in a hospital or clinic by a trained healthcare professional. Ujvira is usually given once every three weeks. Your doctor will adjust the dose or delay treatment if you experience certain side effects. It is very important to follow the treatment schedule exactly as prescribed and not to miss any doses.


    Safety Advice for Ujvira 160 mg Injection

    Breast Feeding

    Breast Feeding

    Unsafe

    This medicine is not safe during breastfeeding as it may harm the baby. Avoid breastfeeding during treatment and for at least 7 months after the last dose.

    Breast Feeding

    Alcohol

    Consult Your Doctor

    It is best to avoid or limit alcohol while receiving Ujvira 160 mg Injection, as alcohol can increase side effects like liver problems, tiredness, or nausea. Always consult your doctor before drinking alcohol during treatment.

    Breast Feeding

    Lungs

    Unsafe

    Ujvira 160 mg Injection may sometimes affect the lungs, causing breathing problems like cough, shortness of breath, or chest discomfort. If you notice any new or worsening breathing issues, inform your doctor right away. Regular check-ups and early reporting of symptoms can help prevent serious lung complications during treatment.

    Breast Feeding

    Driving

    Unsafe

    Ujvira 160 mg Injection may cause side effects like tiredness, dizziness, or vision changes. If you feel unwell or experience these symptoms, avoid driving or operating heavy machines until you feel better. Always check with your doctor before resuming such activities.

    Breast Feeding

    Pregnancy

    Unsafe

    Ujvira 160 mg Injection is not safe to use during pregnancy, as it may harm the unborn baby. Women should use effective birth control during treatment and for a few months after the last dose. If you are pregnant, planning to conceive, or become pregnant while on this medicine, inform your doctor immediately.

    Storage Advice

  • Store in a refrigerator (2 - 8°C)
  • Do not freeze
  • Keep out of reach of children and pets

  • FAQs about Ujvira 160 mg Injection

    Q1. What is Ujvira 160 mg Injection used for?

    Ujvira is used to treat HER2-positive metastatic breast cancer, especially in patients who have already received prior treatment with trastuzumab and chemotherapy.

    Q2. How is Ujvira 160 mg Injection given?

    It is given as an intravenous (IV) infusion by a trained healthcare provider, usually once every three weeks.

    Q3. Can I take Ujvira during pregnancy?

    No. Ujvira should not be used during pregnancy, as it may harm the unborn baby. Use effective contraception during treatment and for 7 months after the last dose.

    Q4. Is Ujvira safe during breastfeeding?

    No. Breastfeeding should be avoided during treatment and for at least 7 months after the final dose.

    Q5. What are the common side effects of Ujvira?

    Common side effects include nausea, fatigue, mouth sores, hair thinning, skin rash, and numbness in hands or feet. Serious side effects like heart or liver problems can also occur.

    Q6. Will I lose my hair during Ujvira treatment?

    Hair thinning or partial hair loss may occur, but complete hair loss is less common compared to traditional chemotherapy.

    Q7. Can Ujvira cause liver or heart problems?

    Yes. Ujvira can affect liver function and heart performance, so regular monitoring is required during treatment.

    Q8. How long will I need to take Ujvira?

    The duration depends on how well your body responds and your doctor’s recommendation. It is typically given in 3-week cycles until disease progression or unacceptable side effects.

    Q9. Can I drive after receiving Ujvira?

    If you feel dizzy or tired, it is best to avoid driving or operating machinery until you feel well again.

    Q10. Will I lose my hair during Ujvira treatment?What precautions should I take while on Ujvira?

    Use contraception, attend regular checkups, report any signs of infection, and inform your doctor about all other medications you're taking.

    Key Fact Box

    Active ingredient TRASTUZUMAB EMTANSINE
    Pharmacologic class Antibody-Drug Conjugates (ADCs)
    Medication category ANTI NEOPLASTICS
    Dosage forms Injection
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