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Sigrima 420mg Injection is a targeted treatment specially designed for HER2-positive breast cancer. It contains pertuzumab, a monoclonal antibody that works by attaching to specific receptors on cancer cells, slowing or stopping their growth. The injection is given into a vein by a healthcare professional, and the dosage depends on your individual condition, whether the cancer is early stage, has come back, or has spread to other parts of the body.
Like most cancer treatments, Sigrima may cause some side effects. Patients often experience tiredness, nausea, diarrhea, or hair loss. It can also affect the bone marrow, which may reduce white blood cell counts and increase the risk of infections. Regular check-ups and blood tests are important during treatment to keep track of your heart, liver, kidney, and blood health. Even if side effects occur, it’s important to continue treatment as advised by your doctor to get the best results.
Before starting Sigrima, let your doctor know if you have heart problems, past radiotherapy, or any allergies. This medicine is not recommended for children, and it should be avoided during pregnancy and breastfeeding. Both men and women are advised to use contraception during and after treatment. When used alongside chemotherapy, Sigrima has been shown to reduce the chances of cancer returning and improve survival outcomes for people with HER2-positive breast cancer.
Sigrima 420mg Injection targets the HER2 protein, which is overexpressed in certain breast cancer cells and promotes their growth. By binding specifically to HER2 receptors on the surface of these cancer cells, Sigrima blocks the transmission of growth signals, thereby inhibiting the proliferation of cancer cells.
Side Effects of Sigrima 420mg Injection
Like all medications, Sigrima 420mg Injection may cause side effects. However, not everyone will experience them.
Serious Side Effects (Seek immediate medical attention):
Note: Always consult your doctor if you experience any unusual symptoms or if common side effects become severe.
Common Side Effects (Usually mild and temporary):
These are usually mild to moderate and may improve as your body adjusts to the treatment:
Initial dose: Sigrima is usually started with a loading dose based on body weight, administered as an intravenous (IV) infusion under medical supervision.
Maintenance dose: After the initial dose, a fixed dose of 420mg is given every 3 weeks as an IV infusion.
The exact dosage and frequency are determined by your doctor based on body weight, treatment phase, and individual response to therapy.
Sigrima is typically used in combination with chemotherapy and administered in a controlled hospital or clinical setting.
Sigrima is not safe during breastfeeding. Use effective contraception during treatment and for at least 7 months after the last dose.
It’s best to avoid alcohol while receiving Sigrima Injection. Drinking alcohol can increase side effects like nausea, fatigue, and liver strain, which may already occur during cancer treatment. If you do drink, always check with your doctor first to ensure it’s safe for your individual health condition.
Sigrima may affect liver function, so regular tests are needed. Tell your doctor if you have liver problems or notice yellow skin, dark urine, or stomach pain.
Sigrima Injection may cause tiredness or dizziness. Avoid driving or operating machines if you feel unwell after treatment.
Sigrima is not safe during pregnancy or breastfeeding. Use effective contraception during treatment and for at least 7 months after the last dose.
Sigrima 420mg Injection is used to treat HER2-positive breast cancer, including early-stage and metastatic (advanced) forms. It works by targeting HER2 receptors on cancer cells and blocking their growth signals.
It is given as an intravenous (IV) infusion under the supervision of a healthcare professional, usually every 3 weeks after the initial loading dose.
Yes, Sigrima may impact heart function, so regular heart monitoring (e.g., echocardiogram) is necessary during treatment.
Yes, Sigrima may impact heart function, so regular heart monitoring (e.g., echocardiogram) is necessary during treatment.
No, it should not be used during pregnancy or breastfeeding. Effective contraception is advised during treatment and for at least 7 months after the last dose.
The duration varies depending on the type and stage of breast cancer and your response to treatment. Your doctor will decide the treatment length.
Always inform your doctor about any other medications or supplements you're taking to avoid potential interactions.
No, Sigrima 420mg Injection is not recommended for use in children or adolescents under 18 years of age.
If you miss a scheduled dose, inform your doctor immediately. Do not try to take the dose on your own.
Hair loss is a possible side effect, especially when Sigrima is used in combination with chemotherapy.
| Active ingredient | Pertuzumab |
| Pharmacologic class | Monoclonal antibody (mAb) |
| Medication category | ANTI NEOPLASTICS |
| Dosage forms | Injection |
Azadine 100mg Injection contains Azacitidine which belongs to the group of medicines called Anticancer agents. It is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).
Azadine 100mg Injection is typically used in adults who cannot undergo stem cell transplantation. It may be also used to treat other conditions, as determined by the doctor.
Azadine Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised.
You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.
Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.
Azadine 100mg Injection is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.
It is used to treat:
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Ques 1: What is the use of AZADINE 100MG INJECTION?
Ans :AZADINE 100MG INJECTION is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).
Ques 2: How does AZADINE 100MG INJECTION works?
Ans :AZADINE 100MG INJECTION is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.
Ques 3: Can I take AZADINE 100MG INJECTION during breastfeeding?
Ans :No. AZADINE 100MG INJECTION is not recommended for use in breast-feeding women. Therefore, inform your doctor before receiving it.
Ques 4: Can AZADINE 100MG INJECTION increase the risk of infections?
Ans :AZADINE 100MG INJECTION may cause a drop in the number of white blood cells in the body and may weaken your immune system. As a result, you may be at a greater risk of getting infected while receiving AZADINE 100MG INJECTION. To avoid this, your doctor will regular monitor your blood counts as a precaution. However, inform your doctor if you experience any signs of infection such as fever.
Ques 5: Can the use of AZADINE 100MG INJECTION make me feel tired?
Ans :Yes. AZADINE 100MG INJECTION may make you feel tired easily. This is because, it reduces the levels of red blood cells in your blood and may make you anemic. Consult your doctor if you experience tiredness after receiving AZADINE 100MG INJECTION. Tiredness can also occur if you have any pre-existing disease conditions such as liver or kidney impairment while receiving this medicine.
Ques 6: Can I drive a car after receiving AZADINE 100MG INJECTION?
Ans :AZADINE 100MG INJECTION may make you feel tired or weak. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by AZADINE 100MG INJECTION.
Ques 7: How AZADINE 100MG INJECTION is administered?
Ans :AZADINE 100MG INJECTION will be given to you only by a doctor or a nurse beneath the skin (subcutaneously) of thighs, arms or abdomen.
Ques 8: How to control nausea caused due to AZADINE 100MG INJECTION?
Ans :Generally, anticancer medicines are associated with uncontrollable nausea and vomiting. To avoid this, your doctor would prescribe a suitable medicine to control them along with AZADINE 100MG INJECTION. If not, consult your doctor for a suitable anti-emetic medicine. Do not self-treat nausea.
Sigrima 420mg Injection is a targeted treatment specially designed for HER2-positive breast cancer. It contains pertuzumab, a monoclonal antibody that works by attaching to specific receptors on cancer cells, slowing or stopping their growth. The injection is given into a vein by a healthcare professional, and the dosage depends on your individual condition, whether the cancer is early stage, has come back, or has spread to other parts of the body.
Like most cancer treatments, Sigrima may cause some side effects. Patients often experience tiredness, nausea, diarrhea, or hair loss. It can also affect the bone marrow, which may reduce white blood cell counts and increase the risk of infections. Regular check-ups and blood tests are important during treatment to keep track of your heart, liver, kidney, and blood health. Even if side effects occur, it’s important to continue treatment as advised by your doctor to get the best results.
Before starting Sigrima, let your doctor know if you have heart problems, past radiotherapy, or any allergies. This medicine is not recommended for children, and it should be avoided during pregnancy and breastfeeding. Both men and women are advised to use contraception during and after treatment. When used alongside chemotherapy, Sigrima has been shown to reduce the chances of cancer returning and improve survival outcomes for people with HER2-positive breast cancer.
Sigrima 420mg Injection targets the HER2 protein, which is overexpressed in certain breast cancer cells and promotes their growth. By binding specifically to HER2 receptors on the surface of these cancer cells, Sigrima blocks the transmission of growth signals, thereby inhibiting the proliferation of cancer cells.
Side Effects of Sigrima 420mg Injection
Like all medications, Sigrima 420mg Injection may cause side effects. However, not everyone will experience them.
Serious Side Effects (Seek immediate medical attention):
Note: Always consult your doctor if you experience any unusual symptoms or if common side effects become severe.
Common Side Effects (Usually mild and temporary):
These are usually mild to moderate and may improve as your body adjusts to the treatment:
Initial dose: Sigrima is usually started with a loading dose based on body weight, administered as an intravenous (IV) infusion under medical supervision.
Maintenance dose: After the initial dose, a fixed dose of 420mg is given every 3 weeks as an IV infusion.
The exact dosage and frequency are determined by your doctor based on body weight, treatment phase, and individual response to therapy.
Sigrima is typically used in combination with chemotherapy and administered in a controlled hospital or clinical setting.
Sigrima is not safe during breastfeeding. Use effective contraception during treatment and for at least 7 months after the last dose.
It’s best to avoid alcohol while receiving Sigrima Injection. Drinking alcohol can increase side effects like nausea, fatigue, and liver strain, which may already occur during cancer treatment. If you do drink, always check with your doctor first to ensure it’s safe for your individual health condition.
Sigrima may affect liver function, so regular tests are needed. Tell your doctor if you have liver problems or notice yellow skin, dark urine, or stomach pain.
Sigrima Injection may cause tiredness or dizziness. Avoid driving or operating machines if you feel unwell after treatment.
Sigrima is not safe during pregnancy or breastfeeding. Use effective contraception during treatment and for at least 7 months after the last dose.
Sigrima 420mg Injection is used to treat HER2-positive breast cancer, including early-stage and metastatic (advanced) forms. It works by targeting HER2 receptors on cancer cells and blocking their growth signals.
It is given as an intravenous (IV) infusion under the supervision of a healthcare professional, usually every 3 weeks after the initial loading dose.
Yes, Sigrima may impact heart function, so regular heart monitoring (e.g., echocardiogram) is necessary during treatment.
Yes, Sigrima may impact heart function, so regular heart monitoring (e.g., echocardiogram) is necessary during treatment.
No, it should not be used during pregnancy or breastfeeding. Effective contraception is advised during treatment and for at least 7 months after the last dose.
The duration varies depending on the type and stage of breast cancer and your response to treatment. Your doctor will decide the treatment length.
Always inform your doctor about any other medications or supplements you're taking to avoid potential interactions.
No, Sigrima 420mg Injection is not recommended for use in children or adolescents under 18 years of age.
If you miss a scheduled dose, inform your doctor immediately. Do not try to take the dose on your own.
Hair loss is a possible side effect, especially when Sigrima is used in combination with chemotherapy.
| Active ingredient | Pertuzumab |
| Pharmacologic class | Monoclonal antibody (mAb) |
| Medication category | ANTI NEOPLASTICS |
| Dosage forms | Injection |
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