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Darbecon 40mcg injection

prescription

Salt Composition

DARBEPOETIN ALFA

Manufacturer

CONCORD BIOTECH LTD

Origin of Medicine

India

₹1200.00

Inclusive of all taxes

Save ₹ 1299 (52%)
MRP:₹2499.00

₹1200.00

    MRP:₹2499.00
Save ₹ 1299 (52%)
1 Prefilled Syringe(s)

1 Prefilled Syringe(s)

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Overview & Usage

Overview

Darbecon 40mcg Injection (PFS) contains Darbepoetin alfa, a medicine from the class of erythropoiesis stimulating agents. It is used to treat symptomatic anemia caused by chronic kidney disease (CKD) in both adults and children. In CKD, kidneys produce less erythropoietin a hormone needed to make red blood cells leading to anemia.

Before starting treatment, your doctor will likely perform blood tests to monitor your response and may adjust your dose accordingly. Blood pressure will also be closely monitored, especially during the early stages of treatment.

This injection is not recommended for patients with uncontrolled high blood pressure. Inform your doctor if you have a history of controlled hypertension, sickle cell anemia, seizures, liver disease, poor response to previous anemia treatments, latex allergy, or hepatitis C.

Use of Darbecon 40mcg Injection should be done with caution in pregnant women, and breastfeeding is not advised during treatment. It is not recommended for infants under 1 month old with CKD. Its safety and effectiveness in children with cancer have not been established, so always consult a pediatrician for guidance.

Common side effects may include increased blood pressure, allergic reactions, pain at the injection site, skin rash, or redness. Contact your doctor if any side effects become severe or persistent.


Usage

1. Treatment of Anemia in Chronic Kidney Disease (CKD):

Darbecon 40mcg Injection is used to treat symptomatic anemia (low red blood cell count) in patients with chronic renal failure, including those on dialysis and those not on dialysis. It helps stimulate the bone marrow to produce more red blood cells by mimicking the action of erythropoietin, a natural hormone usually produced by healthy kidneys.

2. Anemia in Pediatric Patients with CKD:

It is also indicated for use in children with CKD who are experiencing anemia, helping to reduce symptoms such as fatigue, weakness, and shortness of breath.

Pharmacological Effects

Darbecon40mcg Injection contains Darbepoetin alfa, a synthetic form of erythropoietin, a hormone naturally produced by the kidneys. It works by stimulating the bone marrow to produce more red blood cells.

In patients with chronic kidney disease (CKD), the kidneys fail to produce enough erythropoietin, leading to anemia. Darbepoetin alfa binds to the erythropoietin receptors on bone marrow cells, activating them to increase red blood cell production. This helps improve oxygen delivery throughout the body and relieves symptoms of anemia such as tiredness and weakness.


Side Effects

Side Effects of Darbecon 40mcg Injection

Serious Side Effects (Seek immediate medical attention):

  • Severe allergic reactions (swelling of the face or throat, difficulty breathing, severe skin rash) Seizures
  • Blood clots (which may present as chest pain, shortness of breath, leg swelling, or sudden numbness)
  • Contact your doctor immediately if you experience any serious side effects or if any common side effects worsen or persist. Let me know if you need this in a patient friendly leaflet format too.

Common Side Effects (Usually mild and temporary):

  • High blood pressure
  • Pain or discomfort at the injection site
  • Headache
  • Rash or skin redness
  • Joint pain
  • Flu like symptoms (fever, chills, fatigue)

Dosage

The dosage of Darbecon 40mcg Injection (Darbepoetin alfa) depends on the patient's body weight, the severity of anemia, and whether the patient is on dialysis or not. It is usually administered under the supervision of a healthcare professional.

Note: Darbecon Injection should always be used exactly as prescribed. Never self administer or change the dose without consulting your doctor.


Safety Advice For Darbecon 40mcg Injection

Breast Feeding

Breast Feeding

Unsafe

Do not breastfeed while receiving Darbecon, as it is not known if the medicine passes into breast milk and may affect your baby.

Breast Feeding

Alcohol

Consult Your Doctor

There is no known interaction with alcohol, but it’s best to consult your doctor before consuming alcohol while using this medicine.

Breast Feeding

Lungs

Consult Your Doctor

Darbecon Injection may rarely cause breathing issues or lung problems. Seek medical help if you develop chest pain, cough, or shortness of breath, and inform your doctor about any existing lung conditions.

Breast Feeding

Driving

Consult Your Doctor

Darbecon is not likely to affect your ability to drive or use machines. However, if you feel dizzy, tired, or unwell, avoid driving until you feel better.

Breast Feeding

Pregnancy

Safe

Darbecon should be used during pregnancy only if clearly needed. Talk to your doctor about the risks and benefits before starting this medication.

Storage Advice

  • Store in a refrigerator (2 - 8°C)
  • Do not freeze
  • Keep out of reach of children and pets

  • FAQs about Darbecon 40mcg Injection

    Q1. What is Darbecon 40 mcg Injection used for?

    Darbecon 40 mcg Injection is used to treat anemia caused by chronic kidney disease (CKD) in both adults and children. It helps your body make more red blood cells.

    Q2. How does Darbecon work?

    It contains Darbepoetin alfa, which acts like a natural hormone called erythropoietin. It stimulates the bone marrow to produce red blood cells, helping to improve symptoms like tiredness and weakness.

    Q3. How is Darbecon 40 mcg given?

    It is given either under the skin (subcutaneous) or into a vein (intravenous), usually by a doctor or nurse at a hospital or clinic.

    Q4. How often will I need to take this injection?

    The frequency depends on your condition. It is usually given once a week, every two weeks, or even every four weeks, based on your response and whether you are on dialysis.

    Q5.Can I take Darbecon at home?

    In some cases, your doctor may train you or a caregiver to give the injection at home. Always follow medical guidance carefully if doing so.

    Q6. Are there any side effects of Darbecon?

    Common side effects include high blood pressure, injection site pain, rash, and flu-like symptoms. Serious side effects like seizures or allergic reactions are rare but require immediate medical attention.

    Q7. Can pregnant or breastfeeding women use Darbecon?

    Darbecon should be used in pregnancy only if advised by your doctor. Do not breastfeed while using this medicine.

    Q8. Is Darbecon safe for children?

    Yes, it can be used in children with anemia caused by kidney disease, but not in infants under 1 month of age. Safety in children with cancer has not been established.

    Q9. What should I do if I miss a dose?

    If you miss a dose, inform your doctor as soon as possible. Do not double the dose to make up for the missed one.

    Q10. Can I stop using Darbecon if I feel better?

    No. Do not stop the treatment without consulting your doctor, even if you feel better. Stopping it suddenly may cause your anemia to return.

    Key Fact Box

    Active ingredient Darbepoetin alfa
    Pharmacologic class Erythropoiesis-Stimulating Agent (ESA)
    Medication category Hematopoietic Agent
    Dosage forms Injection

    DOSAGE

    Frequently Asked Questions

    Azadine 100mg Injection contains Azacitidine which belongs to the group of medicines called Anticancer agents. It is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Azadine 100mg Injection is typically used in adults who cannot undergo stem cell transplantation. It may be also used to treat other conditions, as determined by the doctor.

    Azadine Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised.

    You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.

    Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.

    MEDICINAL USE OF AZADINE 100MG INJECTION

    Azadine 100mg Injection is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    It is used to treat:

    • All sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow)
    • Chronic myelomonocytic leukemia (CMML; blood cancer of monocytes)
    • Acute myeloid leukemia (AML; blood cancer of WBC)
    SIDE EFFECTS OF AZADINE 100MG INJECTION

    Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

    • Low RBC count causing anemia, tiredness and pale skin
    • Increased infections, lung infections (pneumonia), fever and chills
    • Increased bleeding tendency due to low blood platelet counts
    • Nausea, vomiting
    • Diarrhea, constipation, loss of appetite, stomach pain
    • Tiredness, weakness
    • Injection site reactions (such as pain, redness and swelling or lump formation)
    • Joint pain, muscle pain, skin rashes with redness and itching
    • Sore nose and throat, cold sores, sinnusitis
    • Headache, dizziness
    • Trouble sleeping (insomnia)
    • Nosebleeds, bleeding gums
    • Weight loss
    • Urinary tract infections
    • Ulcers of mouth or tongue
    • High or low blood pressure
    • Anxiety, confusion
    • Hair loss, dehydration
    • Oral fungal infection
    • Sleepiness
    • Fluid around the lungs or heart
    DOSAGE OF AZADINE 100MG INJECTION
    • The dose of Azacitidine is determined by the patient's height, weight, and general condition. It is given under the skin of your thigh, stomach, or upper arm.
    • Minimum of 4 to 6 cycles; may continue treatment if the patient continues to benefit.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified health care professional, the likelihood of a missed dose is very low.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

    Ques 1: What is the use of AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Ques 2: How does AZADINE 100MG INJECTION works?

    Ans :AZADINE 100MG INJECTION is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    Ques 3: Can I take AZADINE 100MG INJECTION during breastfeeding?

    Ans :No. AZADINE 100MG INJECTION is not recommended for use in breast-feeding women. Therefore, inform your doctor before receiving it.

    Ques 4: Can AZADINE 100MG INJECTION increase the risk of infections?

    Ans :AZADINE 100MG INJECTION may cause a drop in the number of white blood cells in the body and may weaken your immune system. As a result, you may be at a greater risk of getting infected while receiving AZADINE 100MG INJECTION. To avoid this, your doctor will regular monitor your blood counts as a precaution. However, inform your doctor if you experience any signs of infection such as fever.

    Ques 5: Can the use of AZADINE 100MG INJECTION make me feel tired?

    Ans :Yes. AZADINE 100MG INJECTION may make you feel tired easily. This is because, it reduces the levels of red blood cells in your blood and may make you anemic. Consult your doctor if you experience tiredness after receiving AZADINE 100MG INJECTION. Tiredness can also occur if you have any pre-existing disease conditions such as liver or kidney impairment while receiving this medicine.

    Ques 6: Can I drive a car after receiving AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION may make you feel tired or weak. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by AZADINE 100MG INJECTION.

    Ques 7: How AZADINE 100MG INJECTION is administered?

    Ans :AZADINE 100MG INJECTION will be given to you only by a doctor or a nurse beneath the skin (subcutaneously) of thighs, arms or abdomen.

    Ques 8: How to control nausea caused due to AZADINE 100MG INJECTION?

    Ans :Generally, anticancer medicines are associated with uncontrollable nausea and vomiting. To avoid this, your doctor would prescribe a suitable medicine to control them along with AZADINE 100MG INJECTION. If not, consult your doctor for a suitable anti-emetic medicine. Do not self-treat nausea.

    Overview

    Darbecon 40mcg Injection (PFS) contains Darbepoetin alfa, a medicine from the class of erythropoiesis stimulating agents. It is used to treat symptomatic anemia caused by chronic kidney disease (CKD) in both adults and children. In CKD, kidneys produce less erythropoietin a hormone needed to make red blood cells leading to anemia.

    Before starting treatment, your doctor will likely perform blood tests to monitor your response and may adjust your dose accordingly. Blood pressure will also be closely monitored, especially during the early stages of treatment.

    This injection is not recommended for patients with uncontrolled high blood pressure. Inform your doctor if you have a history of controlled hypertension, sickle cell anemia, seizures, liver disease, poor response to previous anemia treatments, latex allergy, or hepatitis C.

    Use of Darbecon 40mcg Injection should be done with caution in pregnant women, and breastfeeding is not advised during treatment. It is not recommended for infants under 1 month old with CKD. Its safety and effectiveness in children with cancer have not been established, so always consult a pediatrician for guidance.

    Common side effects may include increased blood pressure, allergic reactions, pain at the injection site, skin rash, or redness. Contact your doctor if any side effects become severe or persistent.


    Usage

    1. Treatment of Anemia in Chronic Kidney Disease (CKD):

    Darbecon 40mcg Injection is used to treat symptomatic anemia (low red blood cell count) in patients with chronic renal failure, including those on dialysis and those not on dialysis. It helps stimulate the bone marrow to produce more red blood cells by mimicking the action of erythropoietin, a natural hormone usually produced by healthy kidneys.

    2. Anemia in Pediatric Patients with CKD:

    It is also indicated for use in children with CKD who are experiencing anemia, helping to reduce symptoms such as fatigue, weakness, and shortness of breath.

    Pharmacological Effects

    Darbecon40mcg Injection contains Darbepoetin alfa, a synthetic form of erythropoietin, a hormone naturally produced by the kidneys. It works by stimulating the bone marrow to produce more red blood cells.

    In patients with chronic kidney disease (CKD), the kidneys fail to produce enough erythropoietin, leading to anemia. Darbepoetin alfa binds to the erythropoietin receptors on bone marrow cells, activating them to increase red blood cell production. This helps improve oxygen delivery throughout the body and relieves symptoms of anemia such as tiredness and weakness.


    Side Effects

    Side Effects of Darbecon 40mcg Injection

    Serious Side Effects (Seek immediate medical attention):

    • Severe allergic reactions (swelling of the face or throat, difficulty breathing, severe skin rash) Seizures
    • Blood clots (which may present as chest pain, shortness of breath, leg swelling, or sudden numbness)
    • Contact your doctor immediately if you experience any serious side effects or if any common side effects worsen or persist. Let me know if you need this in a patient friendly leaflet format too.

    Common Side Effects (Usually mild and temporary):

    • High blood pressure
    • Pain or discomfort at the injection site
    • Headache
    • Rash or skin redness
    • Joint pain
    • Flu like symptoms (fever, chills, fatigue)

    Dosage

    The dosage of Darbecon 40mcg Injection (Darbepoetin alfa) depends on the patient's body weight, the severity of anemia, and whether the patient is on dialysis or not. It is usually administered under the supervision of a healthcare professional.

    Note: Darbecon Injection should always be used exactly as prescribed. Never self administer or change the dose without consulting your doctor.


    Safety Advice For Darbecon 40mcg Injection

    Breast Feeding

    Breast Feeding

    Unsafe

    Do not breastfeed while receiving Darbecon, as it is not known if the medicine passes into breast milk and may affect your baby.

    Breast Feeding

    Alcohol

    Consult Your Doctor

    There is no known interaction with alcohol, but it’s best to consult your doctor before consuming alcohol while using this medicine.

    Breast Feeding

    Lungs

    Consult Your Doctor

    Darbecon Injection may rarely cause breathing issues or lung problems. Seek medical help if you develop chest pain, cough, or shortness of breath, and inform your doctor about any existing lung conditions.

    Breast Feeding

    Driving

    Consult Your Doctor

    Darbecon is not likely to affect your ability to drive or use machines. However, if you feel dizzy, tired, or unwell, avoid driving until you feel better.

    Breast Feeding

    Pregnancy

    Safe

    Darbecon should be used during pregnancy only if clearly needed. Talk to your doctor about the risks and benefits before starting this medication.

    Storage Advice

  • Store in a refrigerator (2 - 8°C)
  • Do not freeze
  • Keep out of reach of children and pets

  • FAQs about Darbecon 40mcg Injection

    Q1. What is Darbecon 40 mcg Injection used for?

    Darbecon 40 mcg Injection is used to treat anemia caused by chronic kidney disease (CKD) in both adults and children. It helps your body make more red blood cells.

    Q2. How does Darbecon work?

    It contains Darbepoetin alfa, which acts like a natural hormone called erythropoietin. It stimulates the bone marrow to produce red blood cells, helping to improve symptoms like tiredness and weakness.

    Q3. How is Darbecon 40 mcg given?

    It is given either under the skin (subcutaneous) or into a vein (intravenous), usually by a doctor or nurse at a hospital or clinic.

    Q4. How often will I need to take this injection?

    The frequency depends on your condition. It is usually given once a week, every two weeks, or even every four weeks, based on your response and whether you are on dialysis.

    Q5.Can I take Darbecon at home?

    In some cases, your doctor may train you or a caregiver to give the injection at home. Always follow medical guidance carefully if doing so.

    Q6. Are there any side effects of Darbecon?

    Common side effects include high blood pressure, injection site pain, rash, and flu-like symptoms. Serious side effects like seizures or allergic reactions are rare but require immediate medical attention.

    Q7. Can pregnant or breastfeeding women use Darbecon?

    Darbecon should be used in pregnancy only if advised by your doctor. Do not breastfeed while using this medicine.

    Q8. Is Darbecon safe for children?

    Yes, it can be used in children with anemia caused by kidney disease, but not in infants under 1 month of age. Safety in children with cancer has not been established.

    Q9. What should I do if I miss a dose?

    If you miss a dose, inform your doctor as soon as possible. Do not double the dose to make up for the missed one.

    Q10. Can I stop using Darbecon if I feel better?

    No. Do not stop the treatment without consulting your doctor, even if you feel better. Stopping it suddenly may cause your anemia to return.

    Key Fact Box

    Active ingredient Darbepoetin alfa
    Pharmacologic class Erythropoiesis-Stimulating Agent (ESA)
    Medication category Hematopoietic Agent
    Dosage forms Injection
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