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Adalipca 40mg Injection

prescription

Salt Composition

ADALIMUMAB

Manufacturer

IPCA LABORATORIES LTD

Origin of Medicine

India

₹8000.00

Inclusive of all taxes

Save ₹ 17000 (68%)
MRP:₹25000.00

₹8000.00

    MRP:₹25000.00
Save ₹ 17000 (68%)
1 Prefilled Syringe(s) Of 0.8ml

1 Prefilled Syringe(s) Of 0.8ml

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Overview & Usage

Overview

Adalipca 40mg Injection is a biologic medication that contains the active ingredient Adalimumab, a monoclonal antibody designed to target and neutralize tumor necrosis factor-alpha (TNF-α), a substance in the body that causes inflammation. It is primarily used in the management of several chronic autoimmune conditions, including rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis, Crohn's disease, and ulcerative colitis. By blocking TNF-α, Adalipca helps reduce inflammation, pain, swelling, and further joint or tissue damage associated with these conditions.

Adalipca 40mg Injection offers a more affordable treatment option without compromising efficacy or safety. The injection is typically administered subcutaneously every two weeks, although dosage frequency may vary based on the specific condition being treated and the patient’s clinical response.

This medication must be used under the supervision of a healthcare professional, and patients are usually monitored regularly for infections, allergic reactions, or changes in blood parameters. Adalipca 40mg Injection has significantly improved the quality of life for many individuals with autoimmune disorders by effectively managing symptoms and slowing disease progression.

Adalipca 40mg Injection (Adalimumab) may cause side effects, though not everyone gets them. Common ones include injection site pain, headache, nausea, fatigue, and mild infections like sore throat or sinusitis. Serious side effects such as severe infections, allergic reactions, liver issues, and changes in blood cell counts may also occur. As it weakens the immune system, Adalipca can increase infection risk and, rarely, certain cancers. Regular medical monitoring is important. Report symptoms like fever, persistent cough, unusual bruising, or yellowing of the skin to your doctor immediately.


Usage

Rheumatoid Arthritis :

Helps reduce joint pain, swelling, and stiffness in adults with this autoimmune joint disorder.

Ankylosing Spondylitis :

Used to relieve symptoms of this chronic inflammatory disease affecting the spine and large joints.

Psoriatic Arthritis:

Manages joint and skin symptoms in patients with this form of arthritis associated with psoriasis.

Juvenile Idiopathic Arthritis:

Used in children over 2 years of age to control joint inflammation and pain.

Plaque Psoriasis :

Treats this skin condition characterized by red, scaly patches by reducing skin inflammation.

Crohn’s Disease :

Helps control inflammation in the digestive tract, relieving symptoms like abdominal pain and diarrhea.

Ulcerative Colitis:

Manages inflammation in the colon and rectum, improving bowel symptoms.

Pharmacological Effects

Adalipca 40mg Injection contains Adalimumab, a specially designed protein known as a monoclonal antibody. It targets and binds to tumor necrosis factor-alpha (TNF-α) — a substance in the body that causes inflammation and plays a major role in autoimmune diseases like rheumatoid arthritis, psoriasis, and inflammatory bowel disease.

By attaching to TNF-α, Adalimumab blocks its interaction with TNF receptors found on immune cells. This action stops the chain of events that leads to inflammation and reduces the number of immune cells moving into inflamed tissues.

As a result, Adalipca 40mg Injection helps to:

  • Reduce inflammation
  • Relieve pain and swelling
  • Protect joints and tissues from further damage
  • Slow the progression of chronic autoimmune diseases
  • This targeted approach makes Adalipca 40mg Injection effective in managing long-term inflammatory conditions.


    Side Effects

    Side Effects of Adalipca 40mg Injection

    Like all medications, Adalipca 40mg Injection may cause side effects. However, not everyone will experience them.

    Serious Side Effects (Seek immediate medical attention):

    • Tuberculosis (TB)
    • Fungal infections
    • Bacterial or viral infections
    • Allergic reactions (rash, itching, swelling, dizziness, difficulty breathing)
    • Liver problems (yellowing of skin or eyes, dark urine)
    • Changes in blood counts (leading to bruising, bleeding, or infections)
    • Nervous system problems (numbness, vision changes, weakness)
    • Heart failure symptoms (shortness of breath, swelling of the ankles)
    • Autoimmune reactions such as lupus-like syndrome
    • Increased risk of certain cancers (very rare)
    • Persistent fever or chills
    • Cough or shortness of breath
    • Unusual bruising or bleeding
    • Yellowing of the skin or eyes
    • Severe abdominal pain
    • Signs of an allergic reaction (swelling, difficulty breathing)

    Common Side Effects (Usually mild and temporary):

    • Pain, redness, or swelling at the injection site
    • Headache
    • Nausea
    • Fatigue
    • Skin rash or itching
    • Abdominal pain or indigestion
    • Fatigue

    Dosage

    The typical adult dosage of this medication varies depending on the condition being treated. For rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis, the recommended dose is 40 mg every other week. In some cases, especially for patients not receiving methotrexate, the dose may be increased to 40 mg once weekly if additional benefit is needed.

    For adults with plaque psoriasis, treatment begins with an initial dose of 80 mg, given as two 40 mg injections on the same day. This is followed by 40 mg every other week, starting one week after the initial dose. This schedule helps achieve and maintain consistent therapeutic levels.

    In Crohn’s disease and ulcerative colitis, the dosing starts with an induction regimen of 160 mg on Day 1 (administered as four 40 mg injections in one day or split over two days), followed by 80 mg on Day 15. The maintenance dose is 40 mg every other week, beginning on Day 29. Depending on the patient’s response, the dose may be adjusted to achieve optimal results.

    For pediatric patients, such as those with juvenile idiopathic arthritis or pediatric Crohn’s disease, dosing is weight-based. A pediatric specialist must carefully determine the appropriate dosage and schedule to ensure safety and effectiveness in children.


    Safety Advice for Adalipca 40mg Injection

    Breast Feeding

    Breast Feeding

    Safe

    Adalipca 40mg Injection can generally be used during breastfeeding. However, always inform your doctor if you are breastfeeding before starting treatment.

    Breast Feeding

    Alcohol

    Consult Your Doctor

    It is not known whether alcohol is safe while using Adalipca 40mg Injection. Consult your doctor for specific advice.

    Breast Feeding

    Lungs

    Consult Your Doctor

    Patients with lung conditions should use Adalipca 40mg Injection carefully. Always inform your doctor about any existing lung problems.

    Breast Feeding

    Driving

    Unsafe

    Adalipca 40mg Injection may cause dizziness, spinning sensations, or vision disturbances. Avoid driving, cycling, or operating heavy machinery if these symptoms occur.

    Breast Feeding

    Pregnancy

    Unsafe

    Do not use Adalipca 40mg Injection during pregnancy unless prescribed by your doctor. Inform your physician if you are pregnant, planning pregnancy, or suspect pregnancy. Effective contraception should be used during treatment and for at least 5 months after the last dose.

    Storage Advice

  • Store in a refrigerator (2 - 8°C)
  • Do not freeze
  • Keep out of reach of children and pets

  • FAQs about Adalipca 40mg Injection

    Q1. What is Adalipca 40mg Injection Injection used for?

    Adalipca is used to treat autoimmune conditions such as rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis, Crohn’s disease, ulcerative colitis, and juvenile idiopathic arthritis. It works by blocking TNF-alpha, a protein responsible for inflammation.

    Q2. How is Adalipca 40mg Injection administered?

    It is given as a subcutaneous injection (under the skin), usually once every two weeks, depending on your condition. It should be administered by a healthcare professional or someone trained to inject at home.

    Q3. Can I inject Adalipca at home?

    Yes, Adalipca is not recommended for people with severe liver problems, as it can further impair liver function. Always inform your doctor about any existing liver conditions before starting this medicine.Yes, after proper training by your doctor or nurse, you can inject Adalipca at home. Always follow the instructions on storage, preparation, and injection sites.

    Q4. What should I do if I miss a dose?

    If you miss a dose, take it as soon as you remember. Then continue your next dose as scheduled. Do not take two doses at once to make up for a missed dose.

    Q5. What are the common side effects of Adalipca ?

    Common side effects include injection site pain, headache, fatigue, nausea, skin rash, and mild respiratory infections. Serious infections may also occur, so report any unusual symptoms to your doctor.

    Q6. Is Adalipca safe during pregnancy or breastfeeding?

    Use during pregnancy or breastfeeding should only be done under a doctor’s supervision. Discuss risks and benefits with your healthcare provider.

    Q7. Can I take vaccines while on Adalipca ?

    Avoid live vaccines while using Adalipca. Inform your doctor about any vaccinations you need before starting treatment.

    Key Fact Box

  • Active ingredient: Adalimumab
  • Pharmacologic class: Monoclonal antibody (mAb)
  • Medication category: antirheumatic agent
  • Dosage forms: Injection
  • References

  • https://en.wikipedia.org/wiki/Adalimumab#History
  • https://versusarthritis.org/about-arthritis/treatments/drugs/adalimumab/
  • . https://www.ncbi.nlm.nih.gov/books/NBK557889/
  • https://medlineplus.gov/druginfo/meds/a603010.html
  • https://go.drugbank.com/drugs/DB00051
  • DOSAGE

    Frequently Asked Questions

    Azadine 100mg Injection contains Azacitidine which belongs to the group of medicines called Anticancer agents. It is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Azadine 100mg Injection is typically used in adults who cannot undergo stem cell transplantation. It may be also used to treat other conditions, as determined by the doctor.

    Azadine Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised.

    You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.

    Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.

    MEDICINAL USE OF AZADINE 100MG INJECTION

    Azadine 100mg Injection is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    It is used to treat:

    • All sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow)
    • Chronic myelomonocytic leukemia (CMML; blood cancer of monocytes)
    • Acute myeloid leukemia (AML; blood cancer of WBC)
    SIDE EFFECTS OF AZADINE 100MG INJECTION

    Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

    • Low RBC count causing anemia, tiredness and pale skin
    • Increased infections, lung infections (pneumonia), fever and chills
    • Increased bleeding tendency due to low blood platelet counts
    • Nausea, vomiting
    • Diarrhea, constipation, loss of appetite, stomach pain
    • Tiredness, weakness
    • Injection site reactions (such as pain, redness and swelling or lump formation)
    • Joint pain, muscle pain, skin rashes with redness and itching
    • Sore nose and throat, cold sores, sinnusitis
    • Headache, dizziness
    • Trouble sleeping (insomnia)
    • Nosebleeds, bleeding gums
    • Weight loss
    • Urinary tract infections
    • Ulcers of mouth or tongue
    • High or low blood pressure
    • Anxiety, confusion
    • Hair loss, dehydration
    • Oral fungal infection
    • Sleepiness
    • Fluid around the lungs or heart
    DOSAGE OF AZADINE 100MG INJECTION
    • The dose of Azacitidine is determined by the patient's height, weight, and general condition. It is given under the skin of your thigh, stomach, or upper arm.
    • Minimum of 4 to 6 cycles; may continue treatment if the patient continues to benefit.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified health care professional, the likelihood of a missed dose is very low.
    • Since Azadine 100 mg Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

    Ques 1: What is the use of AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION is used in adults to treat all sub-types of myelodysplastic syndromes (MDS; group of cancers associated with blood and bone marrow) and certain types of blood cancers known as Chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

    Ques 2: How does AZADINE 100MG INJECTION works?

    Ans :AZADINE 100MG INJECTION is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the cancer cells that is required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of cancer cells and helps the bone marrow to produce normal blood cells.

    Ques 3: Can I take AZADINE 100MG INJECTION during breastfeeding?

    Ans :No. AZADINE 100MG INJECTION is not recommended for use in breast-feeding women. Therefore, inform your doctor before receiving it.

    Ques 4: Can AZADINE 100MG INJECTION increase the risk of infections?

    Ans :AZADINE 100MG INJECTION may cause a drop in the number of white blood cells in the body and may weaken your immune system. As a result, you may be at a greater risk of getting infected while receiving AZADINE 100MG INJECTION. To avoid this, your doctor will regular monitor your blood counts as a precaution. However, inform your doctor if you experience any signs of infection such as fever.

    Ques 5: Can the use of AZADINE 100MG INJECTION make me feel tired?

    Ans :Yes. AZADINE 100MG INJECTION may make you feel tired easily. This is because, it reduces the levels of red blood cells in your blood and may make you anemic. Consult your doctor if you experience tiredness after receiving AZADINE 100MG INJECTION. Tiredness can also occur if you have any pre-existing disease conditions such as liver or kidney impairment while receiving this medicine.

    Ques 6: Can I drive a car after receiving AZADINE 100MG INJECTION?

    Ans :AZADINE 100MG INJECTION may make you feel tired or weak. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by AZADINE 100MG INJECTION.

    Ques 7: How AZADINE 100MG INJECTION is administered?

    Ans :AZADINE 100MG INJECTION will be given to you only by a doctor or a nurse beneath the skin (subcutaneously) of thighs, arms or abdomen.

    Ques 8: How to control nausea caused due to AZADINE 100MG INJECTION?

    Ans :Generally, anticancer medicines are associated with uncontrollable nausea and vomiting. To avoid this, your doctor would prescribe a suitable medicine to control them along with AZADINE 100MG INJECTION. If not, consult your doctor for a suitable anti-emetic medicine. Do not self-treat nausea.

    Overview

    Adalipca 40mg Injection is a biologic medication that contains the active ingredient Adalimumab, a monoclonal antibody designed to target and neutralize tumor necrosis factor-alpha (TNF-α), a substance in the body that causes inflammation. It is primarily used in the management of several chronic autoimmune conditions, including rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis, Crohn's disease, and ulcerative colitis. By blocking TNF-α, Adalipca helps reduce inflammation, pain, swelling, and further joint or tissue damage associated with these conditions.

    Adalipca 40mg Injection offers a more affordable treatment option without compromising efficacy or safety. The injection is typically administered subcutaneously every two weeks, although dosage frequency may vary based on the specific condition being treated and the patient’s clinical response.

    This medication must be used under the supervision of a healthcare professional, and patients are usually monitored regularly for infections, allergic reactions, or changes in blood parameters. Adalipca 40mg Injection has significantly improved the quality of life for many individuals with autoimmune disorders by effectively managing symptoms and slowing disease progression.

    Adalipca 40mg Injection (Adalimumab) may cause side effects, though not everyone gets them. Common ones include injection site pain, headache, nausea, fatigue, and mild infections like sore throat or sinusitis. Serious side effects such as severe infections, allergic reactions, liver issues, and changes in blood cell counts may also occur. As it weakens the immune system, Adalipca can increase infection risk and, rarely, certain cancers. Regular medical monitoring is important. Report symptoms like fever, persistent cough, unusual bruising, or yellowing of the skin to your doctor immediately.


    Usage

    Rheumatoid Arthritis :

    Helps reduce joint pain, swelling, and stiffness in adults with this autoimmune joint disorder.

    Ankylosing Spondylitis :

    Used to relieve symptoms of this chronic inflammatory disease affecting the spine and large joints.

    Psoriatic Arthritis:

    Manages joint and skin symptoms in patients with this form of arthritis associated with psoriasis.

    Juvenile Idiopathic Arthritis:

    Used in children over 2 years of age to control joint inflammation and pain.

    Plaque Psoriasis :

    Treats this skin condition characterized by red, scaly patches by reducing skin inflammation.

    Crohn’s Disease :

    Helps control inflammation in the digestive tract, relieving symptoms like abdominal pain and diarrhea.

    Ulcerative Colitis:

    Manages inflammation in the colon and rectum, improving bowel symptoms.

    Pharmacological Effects

    Adalipca 40mg Injection contains Adalimumab, a specially designed protein known as a monoclonal antibody. It targets and binds to tumor necrosis factor-alpha (TNF-α) — a substance in the body that causes inflammation and plays a major role in autoimmune diseases like rheumatoid arthritis, psoriasis, and inflammatory bowel disease.

    By attaching to TNF-α, Adalimumab blocks its interaction with TNF receptors found on immune cells. This action stops the chain of events that leads to inflammation and reduces the number of immune cells moving into inflamed tissues.

    As a result, Adalipca 40mg Injection helps to:

  • Reduce inflammation
  • Relieve pain and swelling
  • Protect joints and tissues from further damage
  • Slow the progression of chronic autoimmune diseases
  • This targeted approach makes Adalipca 40mg Injection effective in managing long-term inflammatory conditions.


    Side Effects

    Side Effects of Adalipca 40mg Injection

    Like all medications, Adalipca 40mg Injection may cause side effects. However, not everyone will experience them.

    Serious Side Effects (Seek immediate medical attention):

    • Tuberculosis (TB)
    • Fungal infections
    • Bacterial or viral infections
    • Allergic reactions (rash, itching, swelling, dizziness, difficulty breathing)
    • Liver problems (yellowing of skin or eyes, dark urine)
    • Changes in blood counts (leading to bruising, bleeding, or infections)
    • Nervous system problems (numbness, vision changes, weakness)
    • Heart failure symptoms (shortness of breath, swelling of the ankles)
    • Autoimmune reactions such as lupus-like syndrome
    • Increased risk of certain cancers (very rare)
    • Persistent fever or chills
    • Cough or shortness of breath
    • Unusual bruising or bleeding
    • Yellowing of the skin or eyes
    • Severe abdominal pain
    • Signs of an allergic reaction (swelling, difficulty breathing)

    Common Side Effects (Usually mild and temporary):

    • Pain, redness, or swelling at the injection site
    • Headache
    • Nausea
    • Fatigue
    • Skin rash or itching
    • Abdominal pain or indigestion
    • Fatigue

    Dosage

    The typical adult dosage of this medication varies depending on the condition being treated. For rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis, the recommended dose is 40 mg every other week. In some cases, especially for patients not receiving methotrexate, the dose may be increased to 40 mg once weekly if additional benefit is needed.

    For adults with plaque psoriasis, treatment begins with an initial dose of 80 mg, given as two 40 mg injections on the same day. This is followed by 40 mg every other week, starting one week after the initial dose. This schedule helps achieve and maintain consistent therapeutic levels.

    In Crohn’s disease and ulcerative colitis, the dosing starts with an induction regimen of 160 mg on Day 1 (administered as four 40 mg injections in one day or split over two days), followed by 80 mg on Day 15. The maintenance dose is 40 mg every other week, beginning on Day 29. Depending on the patient’s response, the dose may be adjusted to achieve optimal results.

    For pediatric patients, such as those with juvenile idiopathic arthritis or pediatric Crohn’s disease, dosing is weight-based. A pediatric specialist must carefully determine the appropriate dosage and schedule to ensure safety and effectiveness in children.


    Safety Advice for Adalipca 40mg Injection

    Breast Feeding

    Breast Feeding

    Safe

    Adalipca 40mg Injection can generally be used during breastfeeding. However, always inform your doctor if you are breastfeeding before starting treatment.

    Breast Feeding

    Alcohol

    Consult Your Doctor

    It is not known whether alcohol is safe while using Adalipca 40mg Injection. Consult your doctor for specific advice.

    Breast Feeding

    Lungs

    Consult Your Doctor

    Patients with lung conditions should use Adalipca 40mg Injection carefully. Always inform your doctor about any existing lung problems.

    Breast Feeding

    Driving

    Unsafe

    Adalipca 40mg Injection may cause dizziness, spinning sensations, or vision disturbances. Avoid driving, cycling, or operating heavy machinery if these symptoms occur.

    Breast Feeding

    Pregnancy

    Unsafe

    Do not use Adalipca 40mg Injection during pregnancy unless prescribed by your doctor. Inform your physician if you are pregnant, planning pregnancy, or suspect pregnancy. Effective contraception should be used during treatment and for at least 5 months after the last dose.

    Storage Advice

  • Store in a refrigerator (2 - 8°C)
  • Do not freeze
  • Keep out of reach of children and pets

  • FAQs about Adalipca 40mg Injection

    Q1. What is Adalipca 40mg Injection Injection used for?

    Adalipca is used to treat autoimmune conditions such as rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis, Crohn’s disease, ulcerative colitis, and juvenile idiopathic arthritis. It works by blocking TNF-alpha, a protein responsible for inflammation.

    Q2. How is Adalipca 40mg Injection administered?

    It is given as a subcutaneous injection (under the skin), usually once every two weeks, depending on your condition. It should be administered by a healthcare professional or someone trained to inject at home.

    Q3. Can I inject Adalipca at home?

    Yes, Adalipca is not recommended for people with severe liver problems, as it can further impair liver function. Always inform your doctor about any existing liver conditions before starting this medicine.Yes, after proper training by your doctor or nurse, you can inject Adalipca at home. Always follow the instructions on storage, preparation, and injection sites.

    Q4. What should I do if I miss a dose?

    If you miss a dose, take it as soon as you remember. Then continue your next dose as scheduled. Do not take two doses at once to make up for a missed dose.

    Q5. What are the common side effects of Adalipca ?

    Common side effects include injection site pain, headache, fatigue, nausea, skin rash, and mild respiratory infections. Serious infections may also occur, so report any unusual symptoms to your doctor.

    Q6. Is Adalipca safe during pregnancy or breastfeeding?

    Use during pregnancy or breastfeeding should only be done under a doctor’s supervision. Discuss risks and benefits with your healthcare provider.

    Q7. Can I take vaccines while on Adalipca ?

    Avoid live vaccines while using Adalipca. Inform your doctor about any vaccinations you need before starting treatment.

    Key Fact Box

  • Active ingredient: Adalimumab
  • Pharmacologic class: Monoclonal antibody (mAb)
  • Medication category: antirheumatic agent
  • Dosage forms: Injection
  • References

  • https://en.wikipedia.org/wiki/Adalimumab#History
  • https://versusarthritis.org/about-arthritis/treatments/drugs/adalimumab/
  • . https://www.ncbi.nlm.nih.gov/books/NBK557889/
  • https://medlineplus.gov/druginfo/meds/a603010.html
  • https://go.drugbank.com/drugs/DB00051
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