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      Perjeta 420mg Injection


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      Salt Composition

      :     Pertuzumab

      Manufacturer

      :     ROCHE PRODUCTS INDIA PVT LTD

      Origin of Medicine

      :      Switzerland

      Indication

      :     Breast Cancer

      Packaging

      :     1 Vial(S) Of 14ml

      Dosage Form

      :     Injection

      MRP

        :     ₹ 275562

      (Save Upto 40%)

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      Pertuzumab is an antineoplastic agent used in the treatment of HER2-positive metastatic breast cancer in combination with other antineoplastic agents.

      Pertuzumab is a recombinant humanized monoclonal antibody that targets the extracellular dimerization domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2)

      It was first approved by the FDA in 2012 for use with docetaxel and another HER2-targeted monoclonal antibody, trastuzumab, in the treatment of metastatic HER2-positive breast cancer.

      This medicine may reduce the number of blood cells (decrease white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.

      Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.

      MEDICINAL USE OF PERJETA INJECTION
      • HER2-positive breast cancer
      • For metastatic breast cancer Perjeta is used with (trastuzumab) and the chemotherapy medicine, docetaxel. When Perjeta is used before or after surgery, it is used with trastuzumab and chemotherapy medicines.
      SIDE EFFECTS OF PERJETA INJECTION

      Perjeta helps most people with HER2 positive breast cancer, but it may have some unwanted side effects in some people.

      Because Perjeta may be used with other medicines that treat breast cancer, it may be difficult for your doctor to tell whether the side effects are due to Perjeta or due to the other medicines.

      • Diarrhea (loose or frequent stools) or constipation
      • Indigestion or stomach pain
      • Sore mouth, throat or gut
      • Getting tired more easily after light physical activity, such as walking
      • Shortness of breath especially when lying down or being woken from your sleep with shortness of breath
      • Nail problems especially inflammation where the nail meets the skin
      • Hair loss
      • Feeling dizzy, tired, looking pale
      • Hot flushes
      • Frequent infections such as fever, severe chills, sore throat or mouth ulcers
      • Nose bleeds
      DOSAGE USE OF PERJETA INJECTION
      • Perjeta is given by a drip into a vein (intravenous (IV) infusion) once every three weeks.
      • The amount of medicine you are given, and how long the infusion will last, are different for the first and following doses.
      • The first infusion: you will be given 840 mg (two vials) of Perjeta by IV drip over 60 minutes. You will also be given trastuzumab and chemotherapy medicines.
      • For following infusions: if the first infusion was well tolerated, you will be given 420 mg (one vial) of Perjeta by IV drip over 30 - 60 minutes. You will also be given trastuzumab and chemotherapy medicines.
      Ques 1. : Does Perjeta 420mg cause any heart problems?

      Ans : Perjeta 420mg can damage the heart muscle and increase the risk of heart problems. Notify your doctor if you have any history of heart problems.

      Ques 2. : Should I use contraception even after the treatment with Perjeta 420mg?

      Ans : Yes, using contraception during and after treatment with Perjeta 420mg injection for at least six months is necessary.

      Ques 3. : Can Perjeta be self-administered?

      Ans :No, Perjeta should not be self-administered and must be given only under the supervision of a healthcare professional.

      Ques 4. : What should I tell my doctor before taking the Perjeta 420mg injection?

      Ans :Inform your doctor about the history of your high blood pressure, irregular heartbeat, heart failure, and other heart-related problems.

      Ques 5. : Is it okay to take new medication while taking Perjeta 420mg?

      Ans : Inform your doctor about the list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use because certain medications may interact with Perjeta 420mg and reduce effectiveness by causing undesirable side effects.

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