MABTAS 100MG INJECTION


prescription Prescription Required

Salt Composition

:     Rituximab

Manufacturer

:     INTAS PHARMACEUTICALS LTD

Origin of Medicine

:     India

Indication

:     Rheumatoid arthritis, Blood cancer

Packaging

:     1 Vial(S) Of 10ml

Dosage Form

:     Injection

MRP

  :     ₹7389.38

(Save Upto 75%)



Mabtas 100mg Injection contains Rituximab which belongs to the group of medicines called Anticancer drugs. It is used to treat blood cancer (leukemia) and lymph cancer (lymphoma). It can also be used to treat various auto-immune disease conditions such as rheumatoid arthritis, granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) and pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals).

Mabtas 100mg Injection is mostly used in combination with other cytotoxic anticancer agents to achieve better results. It is suitable for use both in adults and in children (aged 6 months or older).

Mabtas 100mg Injection is given as an injection under the supervision of doctor. You must take it in a dose as advised by the doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time.

This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with hepatitis B.

Before taking it, tell your doctor if you have heart disease, liver, or planning surgery or vaccination or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.

This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

MEDICINAL USE OF MABTAS 100MG INJECTION

Mabtas 100mg injection is a monoclonal antibody that targets the antigen CD20 expressed on the cell surface of B-lymphocytes (a type of white blood cells). When this medicine binds to the B-cell, it induces cell death in NHL and CLL.

The binding action blocks cell activation and growth and cause anticancer effects. It inhibits rheumatoid factor production, antigen presentation, T-cell activation, and proinflammatory cytokine production in rheumatoid arthritis.

It is used to treat:

  • Blood cancer (Chronic lymphocytic leukemia)
  • Lymph cancer (Non-Hodgkin’s Lymphoma)
  • Rheumatoid arthritis (joint pain and inflammation)
  • Granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels)
  • Pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals
SIDE EFFECTS OF MABTAS 100MG INJECTION

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine.

  • Increased infections (bacterial, viral or fungal)
  • Low RBC, WBC and platelet counts in blood
  • Nausea, vomiting, diarrhea, stomach pain, constipation, indigestion
  • Mouth ulcers
  • Hair loss
  • Fever, chills, pneumonia, shingles, cold, sinusitis
  • Thrush, urinary tract infection
  • Headache, dizziness, tiredness, weakness
  • Hepatitis B infection
  • High blood sugar and cholesterol levels
  • Weight loss, lack of appetite
  • Numbness, tingling, pricking, burning sensation on the skin
  • Restlessness, problems in falling asleep, anxiety, depression
  • Flushing (skin redness)
  • Eye inflammation or watery eyes
  • Ringing sound in the ears, ear pain
  • Uneven or fast heart rate, high or low blood pressure
  • Shortness of breath, runny nose, nasal itching and repeated sneezing
  • Increased sweating, night sweats
  • Muscle pain, joint pain, back pain, neck pain
  • Pain while passing urine
  • Fungal foot infection (athlete’s foot)
  • Tremors (shakiness)
  • Swelling of the hands or ankles
  • Blood clotting problems
  • Changes in taste
  • Slow heart rate
  • Chest tightness and lung problems
DOSAGE OF MABTAS 100MG INJECTION
  • Mabtas 100mg Injection will be administered to you only by an oncologist or a trained professional into your vein (as intravenous infusion).
  • Rituximab is not given daily. Your schedule will depend on the condition being treated. Follow your doctor's dosing instructions very carefully.
  • Before each injection, you may be given other medications to prevent certain side effects of rituximab.
  • This medicine is usually given in multiple cycles. If you miss a scheduled appointment for receiving a dose of this medicine, call your doctor immediately for further instructions.
  • Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low.
Ques 1: What are the special precautions I should be aware of before starting treatment with Mabtas 100mg injection?

Ans :Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure..

Ques 2: What are Mabtas 100mg infusion-related reactions?

Ans :Infusion reactions occur during or within 24 hours after administering Mabtas 100mg injection. The symptoms are fever, chills, cough, itchy skin, nausea, vomit, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction..

Ques 3: What will be the most important thing to monitor during Mabtas100mg injection?

Ans :Your healthcare professional will monitor you carefully for unwanted side effects during the Mabtas 100mg injection. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Ques 4: Is weight gain a side effect of Mabtas 100mg injection?

Ans :Weight gain has been reported in patients treated with Mabtas N 100mg injection for non-Hodgkin’s lymphoma.

Ques 5: Does Mabtas 100mg injection suppress the immune system?

Ans :Yes, can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking Mabtas 100mg injection because it may cause drug-induced immunosuppression.