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      CARBOKEM NOVO 450MG INJECTION


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      Salt Composition

      :     Carboplatin

      Manufacturer

      :     ALKEM LABORATORIES LTD

      Origin of Medicine

      :     India

      Indication

      :     Lung cancer, Ovarian cancer

      Packaging

      :     1 Vial(S) Of 45ml

      Dosage Form

      :     Injection

      MRP

        :     ₹ 2655

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      Carbokem Novo 450mg injection contains Carboplatin which belongs to the group of medicines called Anti-cancer agents. It is used to treat advanced ovarian cancer and small cell lung cancer. It is generally used in combination with other anti-cancer medicines to achieve better results. Carbokem Novo 450mg injection shows its working by stopping or slowing down the growth of cancer cells.

      Carbokem Novo 450mg Injection is given as an injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. It may take many weeks or months for you to notice or feel the effects, but do not stop taking it until your doctor advises you to do so.

      The use of Carbokem Novo 450MG Injection may cause abnormal decrease in total blood counts. It may also cause nausea, vomiting, mouth sores, hearing loss, loss of taste, tingling or numbness of body parts, increased serum creatinine levels, difficult in passing urine, increased bilirubin levels in the blood and changes in vision.

      You must inform your doctor if you experience allergic reactions with injection such as skin rash, itching, and trouble breathing. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.

      This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

      MEDICINAL USE OF CARBOKEM NOVO 450MG INJECTION

      It is used either alone or in combination with other anticancer medicines to treat:

      • Advanced ovarian cancer (cancer originated in ovary and spread to other parts of the body)
      • Small cell lung carcinoma (lung cancer)

      Carbokem Novo 450mg injection acts as an alkylating agent. This medication reduces the proliferation of cells by inhibiting the formation of DNA, RNA, and proteins, which stops DNA replication and results in programmed cell death.

      SIDE EFFECTS OF CARBOKEM NOVA 450MG INJECTION

      Most side effects do not require any medical attention and disappear as your body adjusts to the medicine.

      • Low blood counts (WBC, RBC, and platelets)
      • Nausea and vomiting
      • Stomach pain and cramps
      • Increased urea levels in the blood
      • Low magnesium, sodium, and potassium levels in the blood
      • Kidney damage, liver damage
      • Tingling, burning, pricking sensation or numbness of body parts
      • Loss of taste
      • Changes in vision
      • Decreased bone movements
      • Ringing in ears, loss of hearing
      • Decreased white blood cell count (neutrophils)
      • Chest tightness or wheezing
      • Diarrhea or constipation
      • Sore lips or mouth ulcers
      • Hair loss
      • Skin rash or itching
      • Back pain, joint pain, and muscle pain
      • Difficulty in urination
      • Extreme tiredness/weakness (asthenia)
      DOSAGE OF CARBOKEM NOVO 450MG INJECTION
      • The dosage of Carbokem Novo 450mg Injection depends on many factors such as the patient age, health, medical condition or history of the patient and many other conditions.
      • SINGLE AGENT THERAPY for use in the treatment of recurrent ovarian cancer: 360 mg/m2 by IV on day 1 every 4 weeks, Usually, single intermittent courses should not be repeated until the neutrophil count is at least 2000 and the platelet count is at least 100,000.
      • COMBINATION THERAPY (with cyclophosphamide) for use in the treatment of advanced ovarian cancer (an effective combination for previously untreated patients): -Carboplatin: 300 mg/m2 by IV on day 1 every 4 weeks for 6 cycles.
      • Cyclophosphamide 600 mg/m2 IV on day 1 every 4 weeks for 6 cycles -Intermittent courses of carboplatin in combination with cyclophosphamide should not be repeated until the neutrophil count is at least 2000 and the platelet count is at least 100,000.
      Ques 1. : Is Carbokem Nova 450mg Injection cell cycle specific?

      Ans : No, Carbokem Nova 450mg Injection is not a cell cycle specific anticancer medication

      Ques 2. : Is Carbokem Nova 450mg Injection FDA approved?

      Ans :Yes, Carbokem Nova 450mg Injection is an FDA approved drug

      Ques 3. : Is it a platinum-based drug?

      Ans :Yes, carboplatin is a platinum-based drug and is effectively used in combination with another drug

      Ques 4. : Does Carbokem Nova 450mg Injection cause neuropathy/ hearing loss/ hair loss/ weight gain/ constipation/ leukemia?

      Ans :Yes, Carbokem Nova 450mg Injection is known to cause side effects like neuropathy, hearing loss, hair loss, weight gain, and constipation. Please inform your doctor about any side-effect that you may observe on taking this drug. Infertility while on therapy may be caused as a side effect of this drug but it may be reverse after stopping the therapy. Yes, Carbokem Nova 450mg Injection may cause leukemia if it is used for a long duration.

      Ques 5. : Is Carbokem Nova 450mg Injection a generic?

      Ans :Yes, Carbokem Nova 450mg Injection is a generic platinum-based compound

      Ques 6. : Is Carbokem Nova 450mg Injection vesicant/cardio-toxic/ anthracycline?

      Ans :No Carbokem Nova 450mg Injection is not cardio-toxic/ anthracycline/vesicant

      Ques 7. : Is Carbokem Nova 450mg Injection used for breast cancer?

      Ans : It is used to treat advanced stage breast cancer

      Ques 8. : Is Carbokem Nova 450mg Injection available in pill form?

      Ans :No Carbokem Nova 450mg Injection is not available in pill form

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